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Genes
ITGA2
Gene - ITGA2
full name
integrin subunit alpha 2
synonyms
BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2, ITGA2, ENSG00000164171
HGNC
HGNC:6137
Entrez Gene
Gene:3673
ENSEMBL
ENSG00000164171
location
chr: 5
start: 52285156
stop: 52390609
strand: +
transcripts
NR_073105.1
NM_002203.3
NR_073106.1
NR_073103.1
NR_073104.1
NR_073107.1
pathways
Arf6 trafficking events
[NCBI:137954]
[Pathway Interaction Database:arf6_traffickingpathway]
[PUBMED:10748097]
[PUBMED:15590645]
[PUBMED:15980073]
[PUBMED:19644450]
[PUBMED:16461286]
[PUBMED:14675422]
[PUBMED:16139226]
[PUBMED:12589044]
[PUBMED:15802264]
[PUBMED:14585928]
[PUBMED:17664335]
[PUBMED:17719203]
[PUBMED:12960436]
[PUBMED:12447393]
[PUBMED:11535619]
[PUBMED:12657640]
[PUBMED:16280360]
[PUBMED:9314528]
[PUBMED:19211056]
[PUBMED:11533043]
[PUBMED:12847086]
[PUBMED:15146059]
[PUBMED:9685333]
[PUBMED:12925709]
[PUBMED:15231847]
[PUBMED:12810696]
[PUBMED:14662749]
[PUBMED:16030257]
[PUBMED:12379803]
[PUBMED:15775968]
[PUBMED:11532961]
[PUBMED:8769418]
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
[NCBI:117293]
[KEGG:hsa05412]
[PUBMED:16823481]
[PUBMED:19205777]
[PUBMED:11716909]
[PUBMED:12270949]
[PUBMED:18382419]
[PUBMED:16101641]
[PUBMED:16124859]
[PUBMED:17413274]
Axon guidance
[NCBI:83065]
[KEGG:hsa04360]
[NCBI:1270303]
[REACTOME:R-HSA-422475]
[PUBMED:14682358]
[PUBMED:15084255]
[PUBMED:11687826]
[PUBMED:15818466]
[PUBMED:15363605]
[PUBMED:12471249]
[PUBMED:15630019]
[PUBMED:11891122]
[PUBMED:15960985]
[PUBMED:12677003]
CHL1 interactions
[NCBI:1270327]
[REACTOME:R-HSA-447041]
[PUBMED:10662501]
[PUBMED:19356150]
CXCR4-mediated signaling events
[NCBI:137910]
[Pathway Interaction Database:cxcr4_pathway]
[PUBMED:18799424]
[PUBMED:17537990]
[PUBMED:10881171]
[PUBMED:17675482]
[PUBMED:11157475]
[PUBMED:12077227]
[PUBMED:11544290]
[PUBMED:8752280]
[PUBMED:12535795]
[PUBMED:19380820]
[PUBMED:10952719]
[PUBMED:16230460]
[PUBMED:12682230]
[PUBMED:16503409]
[PUBMED:10644702]
[PUBMED:9722546]
[PUBMED:11784854]
[PUBMED:10491003]
[PUBMED:10521508]
[PUBMED:10606629]
[PUBMED:15615703]
[PUBMED:17568820]
[PUBMED:10753828]
[PUBMED:12519755]
[PUBMED:12032308]
[PUBMED:8752281]
[PUBMED:10570282]
[PUBMED:11369622]
[PUBMED:15728464]
[PUBMED:12590707]
[PUBMED:16038794]
[PUBMED:14662753]
[PUBMED:18596232]
[PUBMED:17056591]
[PUBMED:14602072]
[PUBMED:15994292]
[PUBMED:16919488]
[PUBMED:15872091]
[PUBMED:10506573]
[PUBMED:12036857]
[PUBMED:15618472]
[PUBMED:14704365]
[PUBMED:18227351]
[PUBMED:11641392]
[PUBMED:18319399]
[PUBMED:12133960]
[PUBMED:15630457]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
Dilated cardiomyopathy
[NCBI:121494]
[KEGG:hsa05414]
[PUBMED:11524405]
[PUBMED:11805847]
[PUBMED:12270949]
[PUBMED:14522402]
[PUBMED:19017683]
[PUBMED:15146239]
[PUBMED:18672201]
[PUBMED:19273156]
[PUBMED:19246813]
[PUBMED:11716909]
[PUBMED:16817756]
ECM proteoglycans
[NCBI:1270256]
[REACTOME:R-HSA-3000178]
[PUBMED:20301236]
[PUBMED:21307119]
ECM-receptor interaction
[NCBI:83068]
[KEGG:hsa04512]
[PUBMED:7698997]
[PUBMED:15381249]
[PUBMED:12796473]
[PUBMED:11331578]
[PUBMED:15036264]
[PUBMED:12125070]
[PUBMED:12736199]
[PUBMED:15229478]
[PUBMED:11572082]
[PUBMED:10617638]
[PUBMED:12845610]
[PUBMED:12921709]
Extracellular matrix organization
[NCBI:1270244]
[REACTOME:R-HSA-1474244]
[PUBMED:21123617]
[PUBMED:21917992]
[PUBMED:12845610]
Focal adhesion
[NCBI:83067]
[KEGG:hsa04510]
[PUBMED:10698680]
[PUBMED:15459662]
[PUBMED:14756624]
[PUBMED:11573199]
[PUBMED:12640026]
[PUBMED:15179030]
[PUBMED:15108811]
[PUBMED:15053919]
[PUBMED:11082269]
[PUBMED:15034601]
[PUBMED:12235283]
[PUBMED:14519391]
[PUBMED:11146675]
[PUBMED:11229600]
[PUBMED:15688067]
[PUBMED:14744429]
[PUBMED:11882383]
Hematopoietic cell lineage
[NCBI:83078]
[KEGG:hsa04640]
[PUBMED:15629410]
[PUBMED:15738953]
[PUBMED:11905810]
[PUBMED:15156179]
[PUBMED:12415312]
[PUBMED:14985712]
[PUBMED:9927518]
[PUBMED:15771582]
[PUBMED:14670296]
[PUBMED:12360214]
Hemostasis
[NCBI:1269340]
[REACTOME:R-HSA-109582]
Hypertrophic cardiomyopathy (HCM)
[NCBI:114229]
[KEGG:hsa05410]
[PUBMED:11805847]
[PUBMED:18572189]
[PUBMED:14711353]
[PUBMED:19136482]
[PUBMED:18056765]
[PUBMED:11225594]
[PUBMED:12844200]
[PUBMED:10615904]
[PUBMED:11716909]
[PUBMED:11371514]
[PUBMED:12270949]
Integrin cell surface interactions
[NCBI:1270260]
[REACTOME:R-HSA-216083]
[PUBMED:10215583]
[PUBMED:15147720]
[PUBMED:12231361]
[PUBMED:8866399]
[PUBMED:19273203]
L1CAM interactions
[NCBI:1270323]
[REACTOME:R-HSA-373760]
[PUBMED:9211984]
[PUBMED:18760361]
[PUBMED:14709786]
[PUBMED:17189949]
[PUBMED:19356150]
Laminin interactions
[NCBI:1270253]
[REACTOME:R-HSA-3000157]
[PUBMED:23057746]
MET activates PTK2 signaling
[NCBI:1457800]
[REACTOME:R-HSA-8874081]
[PUBMED:17574028]
[PUBMED:24480479]
[PUBMED:11478803]
[PUBMED:16782899]
[PUBMED:10521801]
[PUBMED:20802513]
MET promotes cell motility
[NCBI:1457799]
[REACTOME:R-HSA-8875878]
[PUBMED:24518591]
[PUBMED:8384622]
[PUBMED:10521801]
[PUBMED:12006644]
[PUBMED:10753869]
[PUBMED:11478803]
[PUBMED:16849525]
[PUBMED:24814316]
[PUBMED:16782899]
Non-integrin membrane-ECM interactions
[NCBI:1270254]
[REACTOME:R-HSA-3000171]
[PUBMED:15039999]
[PUBMED:20565253]
PI3K-Akt signaling pathway
[NCBI:692234]
[KEGG:hsa04151]
[PUBMED:12048182]
[PUBMED:11357143]
[PUBMED:21440011]
[PUBMED:15209374]
[PUBMED:12669022]
[PUBMED:18842113]
[PUBMED:16847462]
[PUBMED:12660731]
[PUBMED:17360849]
[PUBMED:9838078]
[PUBMED:15505410]
[PUBMED:16248975]
[PUBMED:12531180]
[PUBMED:21779440]
[PUBMED:16187290]
[PUBMED:15784165]
[PUBMED:21620960]
Pathways in cancer
[NCBI:83105]
[KEGG:hsa05200]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16899407]
[PUBMED:12621137]
[PUBMED:21193867]
[PUBMED:16001072]
[PUBMED:11707511]
[PUBMED:11253051]
[PUBMED:11071626]
[PUBMED:17251915]
[PUBMED:11736900]
[PUBMED:16557281]
[PUBMED:16699851]
[PUBMED:16189702]
[PUBMED:11902573]
[PUBMED:16555243]
[PUBMED:8069858]
[PUBMED:15310786]
[PUBMED:9834202]
[PUBMED:16700615]
[PUBMED:12545153]
[PUBMED:15656799]
[PUBMED:12154354]
[PUBMED:11895903]
[PUBMED:11527574]
[PUBMED:16326109]
[PUBMED:16339096]
[PUBMED:11160144]
[PUBMED:15724144]
[PUBMED:12951584]
[PUBMED:10647931]
[PUBMED:16881963]
[PUBMED:15557758]
[PUBMED:11477132]
[PUBMED:15721476]
[PUBMED:15625120]
[PUBMED:16236521]
[PUBMED:14967450]
[PUBMED:15942304]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15573119]
[PUBMED:15009714]
[PUBMED:16112428]
[PUBMED:15611513]
[PUBMED:16001050]
[PUBMED:15349822]
[PUBMED:16551846]
[PUBMED:15978322]
[PUBMED:15774796]
[PUBMED:16352814]
[PUBMED:12951588]
[PUBMED:10944551]
[PUBMED:10740269]
[PUBMED:15639402]
[PUBMED:12407699]
[PUBMED:11130178]
[PUBMED:15109562]
[PUBMED:11170304]
[PUBMED:11276000]
[PUBMED:9643506]
[PUBMED:16248975]
[PUBMED:16242838]
[PUBMED:12946833]
[PUBMED:11559746]
[PUBMED:9196022]
[PUBMED:12079267]
[PUBMED:15468170]
[PUBMED:16064138]
[PUBMED:14580692]
[PUBMED:15082523]
[PUBMED:15551095]
[PUBMED:17062879]
[PUBMED:17211469]
[PUBMED:11720739]
[PUBMED:12588368]
[PUBMED:11057895]
[PUBMED:9422516]
[PUBMED:12894244]
[PUBMED:15479695]
[PUBMED:16189154]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11103787]
[PUBMED:15122209]
[PUBMED:12711111]
[PUBMED:12243753]
[PUBMED:16306523]
[PUBMED:16702400]
[PUBMED:15270885]
[PUBMED:14685170]
[PUBMED:14586404]
[PUBMED:11078609]
[PUBMED:15284264]
[PUBMED:10505543]
[PUBMED:11223406]
[PUBMED:14982876]
[PUBMED:12648469]
[PUBMED:12867060]
[PUBMED:15711891]
[PUBMED:12094241]
[PUBMED:16642045]
[PUBMED:11463388]
[PUBMED:12762887]
[PUBMED:15746962]
[PUBMED:15823750]
[PUBMED:16750612]
[PUBMED:16484590]
[PUBMED:11459867]
[PUBMED:16146838]
[PUBMED:14556242]
[PUBMED:15947972]
[PUBMED:12563308]
[PUBMED:16946003]
[PUBMED:15948971]
[PUBMED:11407945]
[PUBMED:12737309]
[PUBMED:16095998]
[PUBMED:12351585]
[PUBMED:24508914]
[PUBMED:12084351]
[PUBMED:11807782]
[PUBMED:14695152]
[PUBMED:10453277]
[PUBMED:17554387]
[PUBMED:15841168]
[PUBMED:12616528]
[PUBMED:10403855]
[PUBMED:16054233]
[PUBMED:16474624]
[PUBMED:16822996]
[PUBMED:17028294]
[PUBMED:11224709]
[PUBMED:11750244]
[PUBMED:11905738]
[PUBMED:15719031]
[PUBMED:10843728]
[PUBMED:16110317]
[PUBMED:11721960]
[PUBMED:12741677]
[PUBMED:7585656]
[PUBMED:12801837]
[PUBMED:16551847]
[PUBMED:12459728]
[PUBMED:11431710]
[PUBMED:12468433]
[PUBMED:11165748]
[PUBMED:16042571]
[PUBMED:16508724]
[PUBMED:15000146]
[PUBMED:17149381]
[PUBMED:15948711]
[PUBMED:14747944]
[PUBMED:14737121]
[PUBMED:12379883]
[PUBMED:17158541]
[PUBMED:12850530]
[PUBMED:10835690]
[PUBMED:16870043]
Phagosome
[NCBI:153910]
[KEGG:hsa04145]
[PUBMED:17637737]
[PUBMED:18513324]
[PUBMED:15894272]
[PUBMED:10684585]
[PUBMED:18492791]
[PUBMED:15036145]
[PUBMED:17245426]
Platelet Adhesion to exposed collagen
[NCBI:1269349]
[REACTOME:R-HSA-75892]
[PUBMED:12356768]
[PUBMED:9295288]
Platelet activation
[NCBI:952858]
[KEGG:hsa04611]
[PUBMED:20002545]
[PUBMED:18363565]
[PUBMED:18544684]
[PUBMED:18174460]
[PUBMED:23106920]
[PUBMED:18550847]
[PUBMED:22119499]
[PUBMED:19630797]
[PUBMED:19286885]
[PUBMED:17158345]
[PUBMED:20089227]
[PUBMED:22701130]
[PUBMED:21071698]
[PUBMED:23805129]
[PUBMED:16149014]
[PUBMED:18641368]
Proteoglycans in cancer
[NCBI:782000]
[KEGG:hsa05205]
[PUBMED:19433454]
[PUBMED:20655987]
[PUBMED:18798267]
[PUBMED:10633082]
[PUBMED:10687947]
[PUBMED:22735579]
[PUBMED:24412155]
[PUBMED:9346940]
[PUBMED:22087031]
[PUBMED:22194599]
[PUBMED:14711376]
[PUBMED:19255147]
[PUBMED:15655247]
[PUBMED:11717317]
[PUBMED:17971838]
[PUBMED:18413366]
[PUBMED:20974860]
[PUBMED:11830493]
[PUBMED:23058688]
[PUBMED:18450475]
[PUBMED:12748184]
[PUBMED:19733083]
[PUBMED:18812315]
[PUBMED:12509413]
[PUBMED:21155971]
[PUBMED:11931647]
[PUBMED:18949819]
[PUBMED:12729888]
[PUBMED:15994311]
[PUBMED:23305321]
[PUBMED:18505598]
[PUBMED:22563565]
[PUBMED:22033227]
Regulation of actin cytoskeleton
[NCBI:83089]
[KEGG:hsa04810]
[PUBMED:11152757]
[PUBMED:11082272]
[PUBMED:10574699]
[PUBMED:11082269]
[PUBMED:14657486]
[PUBMED:14744429]
[PUBMED:12700767]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by MET
[NCBI:1457794]
[REACTOME:R-HSA-6806834]
[PUBMED:1846706]
[PUBMED:12948444]
[PUBMED:16782899]
[PUBMED:15249655]
[PUBMED:22270953]
[PUBMED:15167892]
[PUBMED:7708691]
[PUBMED:11081636]
[PUBMED:8384622]
[PUBMED:21102609]
[PUBMED:16461907]
[PUBMED:9407027]
[PUBMED:7854453]
[PUBMED:7651534]
[PUBMED:9070211]
[PUBMED:8208547]
[PUBMED:24518591]
[PUBMED:6590967]
[PUBMED:15180923]
[PUBMED:20802513]
[PUBMED:10521801]
[PUBMED:9038378]
[PUBMED:17403932]
[PUBMED:1655790]
[PUBMED:12006644]
[PUBMED:7513258]
[PUBMED:18614017]
[PUBMED:10753869]
[PUBMED:17662939]
[PUBMED:14685170]
[PUBMED:10734310]
[PUBMED:1827664]
[PUBMED:7731718]
[PUBMED:19996456]
[PUBMED:11430831]
[PUBMED:8302603]
[PUBMED:15218027]
[PUBMED:9140397]
[PUBMED:2423252]
[PUBMED:16113677]
[PUBMED:12147692]
[PUBMED:10648629]
[PUBMED:7854452]
[PUBMED:15070743]
[PUBMED:15301554]
[PUBMED:19881549]
[PUBMED:25992381]
[PUBMED:10871282]
[PUBMED:12726861]
Small cell lung cancer
[NCBI:83118]
[KEGG:hsa05222]
[PUBMED:12711111]
[PUBMED:11463388]
[PUBMED:12741677]
[PUBMED:11905738]
[PUBMED:11807782]
[PUBMED:12379883]
[PUBMED:12243753]
[PUBMED:12616528]
[PUBMED:11720739]
[PUBMED:15109562]
[PUBMED:12407699]
[PUBMED:10944551]
[PUBMED:16112428]
[PUBMED:11559746]
[PUBMED:16064138]
[PUBMED:11902573]
Syndecan interactions
[NCBI:1270255]
[REACTOME:R-HSA-3000170]
[PUBMED:17097330]
[PUBMED:15774861]
[PUBMED:20565253]
Syndecan-2-mediated signaling events
[NCBI:138031]
[Pathway Interaction Database:syndecan_2_pathway]
[PUBMED:17623663]
[PUBMED:11373281]
[PUBMED:16357320]
[PUBMED:12507425]
[PUBMED:16945929]
[PUBMED:14976204]
[PUBMED:10772816]
[PUBMED:10843988]
[PUBMED:8528141]
[PUBMED:15936998]
[PUBMED:10734053]
[PUBMED:11179419]
[PUBMED:9660868]
[PUBMED:16198615]
[PUBMED:9660869]
[PUBMED:15752734]
[PUBMED:10446183]
[PUBMED:11580899]
[PUBMED:17548511]
[PUBMED:11931647]
[PUBMED:16139226]
[PUBMED:16008343]
[PUBMED:14527339]
[PUBMED:16997272]
[PUBMED:10639336]
[PUBMED:16440330]
[PUBMED:11018053]
[PUBMED:10704377]
[PUBMED:9244383]
[PUBMED:12860416]
VEGFR3 signaling in lymphatic endothelium
[NCBI:137996]
[Pathway Interaction Database:lymphangiogenesis_pathway]
[PUBMED:12881528]
[PUBMED:8617204]
[PUBMED:10449752]
[PUBMED:9247316]
[PUBMED:11335727]
[PUBMED:9012504]
[PUBMED:9435229]
[PUBMED:16076871]
[PUBMED:11532940]
[PUBMED:9927207]
[PUBMED:11553610]
[PUBMED:7675451]
[PUBMED:8662748]
[PUBMED:16633338]