full name
ERCC excision repair 8, CSA ubiquitin ligase complex subunit

synonyms
CKN1, CSA, UVSS2, ERCC8, ENSG00000049167

HGNC
HGNC:3439

Entrez Gene
Gene:1161

ENSEMBL
ENSG00000049167

location
chr: 5
start: 60169659
stop: 60240905
strand: -

OMIM
OMIM:609412: ERCC8 (Autosomal recessive inheritance)
OMIM:216400: Cockayne syndrome, type A
OMIM:614621: UV-sensitive syndrome 2

transcripts
NM_000082.3

pathways
DNA Repair [NCBI:1270350] [REACTOME:R-HSA-73894] [PUBMED:10583946] [PUBMED:23175119]
Dual incision in TC-NER [NCBI:1309119] [REACTOME:R-HSA-6782135] [PUBMED:19279666] [PUBMED:23906714] [PUBMED:8078911] [PUBMED:16246722] [PUBMED:19023283] [PUBMED:11904382] [PUBMED:24402227]
Formation of TC-NER Pre-Incision Complex [NCBI:1309118] [REACTOME:R-HSA-6781823] [PUBMED:12208738] [PUBMED:16916636] [PUBMED:17290000] [PUBMED:25435140] [PUBMED:22466611] [PUBMED:10944529] [PUBMED:22902626] [PUBMED:16751180] [PUBMED:22466610] [PUBMED:8876179] [PUBMED:12660172] [PUBMED:25154395] [PUBMED:8078911]
Gap-filling DNA repair synthesis and ligation in TC-NER [NCBI:1309120] [REACTOME:R-HSA-6782210] [PUBMED:20227374] [PUBMED:19279666] [PUBMED:17643379]
Nucleotide Excision Repair [NCBI:1309111] [REACTOME:R-HSA-5696398] [PUBMED:11900249] [PUBMED:23906714] [PUBMED:14599765] [PUBMED:10583946] [PUBMED:24954209] [PUBMED:19023283]
Nucleotide excision repair [NCBI:83044] [KEGG:hsa03420] [PUBMED:11436323] [PUBMED:18018633] [PUBMED:11436316] [PUBMED:17884153] [PUBMED:11436314] [PUBMED:17276014] [PUBMED:16922398]
Transcription-Coupled Nucleotide Excision Repair (TC-NER) [NCBI:1309117] [REACTOME:R-HSA-6781827] [PUBMED:24954209] [PUBMED:11823795] [PUBMED:19023283] [PUBMED:23906714] [PUBMED:3466163]
Ubiquitin mediated proteolysis [NCBI:83056] [KEGG:hsa04120] [PUBMED:16405856] [PUBMED:12944364] [PUBMED:16922408] [PUBMED:17588513] [PUBMED:16922367] [PUBMED:16922370] [PUBMED:16816840]