full name
cyclin dependent kinase inhibitor 2C

synonyms
INK4C, p18, p18-INK4C, CDKN2C, ENSG00000123080

HGNC
HGNC:1789

Entrez Gene
Gene:1031

ENSEMBL
ENSG00000123080

location
chr: 1
start: 51434367
stop: 51440309
strand: +

transcripts
NM_001262.2
NM_078626.2

pathways
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic [NCBI:1269763] [REACTOME:R-HSA-69278]
Cell cycle [NCBI:83054] [KEGG:hsa04110] [PUBMED:7973727] [PUBMED:17568790] [PUBMED:9832503] [PUBMED:16936746] [PUBMED:9029154] [PUBMED:12573239] [PUBMED:19020303] [PUBMED:9618481] [PUBMED:12809600] [PUBMED:8242749] [PUBMED:10385618] [PUBMED:17426725] [PUBMED:17018296] [PUBMED:16212951] [PUBMED:12925736] [PUBMED:11099028] [PUBMED:15568976] [PUBMED:15838516] [PUBMED:15838523] [PUBMED:15876871] [PUBMED:7908906] [PUBMED:9889196]
Cellular Senescence [NCBI:1270426] [REACTOME:R-HSA-2559583] [PUBMED:21078816] [PUBMED:18711403] [PUBMED:22048312] [PUBMED:19818705] [PUBMED:17662938] [PUBMED:23746838] [PUBMED:9282108] [PUBMED:17667954] [PUBMED:13905658]
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
Cyclin D associated events in G1 [NCBI:1269767] [REACTOME:R-HSA-69231]
E2F transcription factor network [NCBI:137934] [Pathway Interaction Database:e2f_pathway] [PUBMED:15175242] [PUBMED:11034215] [PUBMED:8832394] [PUBMED:7479977] [PUBMED:12077144] [PUBMED:11274364] [PUBMED:8618861] [PUBMED:11857079] [PUBMED:7958837] [PUBMED:15014447] [PUBMED:9774682] [PUBMED:9704927] [PUBMED:9271400] [PUBMED:8334989] [PUBMED:16288221] [PUBMED:10766737] [PUBMED:8657141] [PUBMED:8552092] [PUBMED:11101847] [PUBMED:12757710] [PUBMED:17704056] [PUBMED:7705662] [PUBMED:15897886] [PUBMED:9192872] [PUBMED:9778043] [PUBMED:12766778] [PUBMED:15510213] [PUBMED:11418595] [PUBMED:10454584] [PUBMED:10783242] [PUBMED:11904439] [PUBMED:16179649] [PUBMED:7791762] [PUBMED:11719808] [PUBMED:12389032] [PUBMED:8264596] [PUBMED:19491197] [PUBMED:15713665] [PUBMED:16357170] [PUBMED:9689056] [PUBMED:12748276] [PUBMED:2524830] [PUBMED:14633988] [PUBMED:12697828] [PUBMED:12101096] [PUBMED:11799067] [PUBMED:15133492] [PUBMED:16892051] [PUBMED:8943353] [PUBMED:9724731] [PUBMED:10030670] [PUBMED:11459832] [PUBMED:8114719] [PUBMED:9520412] [PUBMED:18348985] [PUBMED:9020173] [PUBMED:11389439] [PUBMED:16211008] [PUBMED:12411495] [PUBMED:7958836] [PUBMED:12909625] [PUBMED:15306814] [PUBMED:10688648] [PUBMED:12611887] [PUBMED:9191053] [PUBMED:10373518] [PUBMED:10187822]
Endocrine resistance [NCBI:1404799] [KEGG:hsa01522] [PUBMED:24415977] [PUBMED:23625614] [PUBMED:24841429] [PUBMED:15613444] [PUBMED:23714450] [PUBMED:20960099] [PUBMED:22771991] [PUBMED:19701242] [PUBMED:24289103] [PUBMED:24130921] [PUBMED:23344024] [PUBMED:22015292] [PUBMED:26122181] [PUBMED:26473850] [PUBMED:18804516] [PUBMED:24565562] [PUBMED:26849149] [PUBMED:25907219] [PUBMED:20887199]
G1 Phase [NCBI:1269766] [REACTOME:R-HSA-69236]
HTLV-I infection [NCBI:373901] [KEGG:hsa05166] [PUBMED:17446673] [PUBMED:16436385] [PUBMED:14686485] [PUBMED:19861996] [PUBMED:19092975] [PUBMED:11325603] [PUBMED:16155602] [PUBMED:12910251] [PUBMED:16155605] [PUBMED:16036567] [PUBMED:11244044] [PUBMED:18702816] [PUBMED:15569630] [PUBMED:21114861] [PUBMED:16155611] [PUBMED:17384582] [PUBMED:16155608] [PUBMED:10602469] [PUBMED:19014483] [PUBMED:9325311]
Mitotic G1-G1/S phases [NCBI:1269764] [REACTOME:R-HSA-453279]
Oncogene Induced Senescence [NCBI:1270427] [REACTOME:R-HSA-2559585] [PUBMED:10722742] [PUBMED:20583212] [PUBMED:8521522] [PUBMED:20534573] [PUBMED:11234019] [PUBMED:14729966] [PUBMED:12839923] [PUBMED:8319905] [PUBMED:18365017] [PUBMED:15572696] [PUBMED:9529249] [PUBMED:10733595] [PUBMED:9824166] [PUBMED:11782450] [PUBMED:8259215] [PUBMED:7588608] [PUBMED:8552081] [PUBMED:9704925] [PUBMED:22336108] [PUBMED:11883935]
Oxidative Stress Induced Senescence [NCBI:1270428] [REACTOME:R-HSA-2559580] [PUBMED:17344414] [PUBMED:17332741] [PUBMED:8622688] [PUBMED:7588633] [PUBMED:15563468] [PUBMED:15287722] [PUBMED:11062067] [PUBMED:16337592] [PUBMED:14532106] [PUBMED:17254968] [PUBMED:15866172] [PUBMED:9628874] [PUBMED:12171911] [PUBMED:7816143] [PUBMED:22020331] [PUBMED:11564866] [PUBMED:9162092] [PUBMED:8974401] [PUBMED:19451217] [PUBMED:12808055] [PUBMED:17210787] [PUBMED:8846784] [PUBMED:19462008] [PUBMED:12134156] [PUBMED:8626550] [PUBMED:8774846] [PUBMED:12189133] [PUBMED:9195981] [PUBMED:8622669] [PUBMED:8259215] [PUBMED:19528227] [PUBMED:9564042] [PUBMED:9529249] [PUBMED:16436515] [PUBMED:19451218] [PUBMED:17395714] [PUBMED:9030721] [PUBMED:12435631] [PUBMED:22325352]
Senescence-Associated Secretory Phenotype (SASP) [NCBI:1270431] [REACTOME:R-HSA-2559582] [PUBMED:18411265] [PUBMED:21979375] [PUBMED:18267069] [PUBMED:19597488] [PUBMED:19218920] [PUBMED:20818427] [PUBMED:11114305] [PUBMED:8617720] [PUBMED:22178396] [PUBMED:19805069] [PUBMED:23770676] [PUBMED:8384717] [PUBMED:18555777] [PUBMED:21686281] [PUBMED:20351173] [PUBMED:8688489] [PUBMED:19053174] [PUBMED:8234276] [PUBMED:18555778]
Transcriptional misregulation in cancer [NCBI:523016] [KEGG:hsa05202] [PUBMED:17327229] [PUBMED:20190806] [PUBMED:20145147] [PUBMED:11313274] [PUBMED:11863357] [PUBMED:19472090] [PUBMED:18330902] [PUBMED:19738075] [PUBMED:15024077] [PUBMED:12032780] [PUBMED:14630078] [PUBMED:21765642] [PUBMED:19564705] [PUBMED:17101797] [PUBMED:15160934] [PUBMED:15688424] [PUBMED:15985538] [PUBMED:12527902] [PUBMED:12511414] [PUBMED:11607818] [PUBMED:17222504] [PUBMED:15826838] [PUBMED:21747944] [PUBMED:19406209] [PUBMED:10350329] [PUBMED:21779514] [PUBMED:18563191] [PUBMED:16946003] [PUBMED:17250957] [PUBMED:12670461] [PUBMED:12529654] [PUBMED:18855877] [PUBMED:17505060] [PUBMED:20153925] [PUBMED:20490326] [PUBMED:12130514] [PUBMED:18648544] [PUBMED:19855079] [PUBMED:10717473] [PUBMED:20478527] [PUBMED:11340171] [PUBMED:16169901] [PUBMED:14998494] [PUBMED:19233641] [PUBMED:19133982] [PUBMED:12393465] [PUBMED:19059936] [PUBMED:18172298] [PUBMED:10500199] [PUBMED:19141473] [PUBMED:10537274] [PUBMED:15156184] [PUBMED:14701735] [PUBMED:19422821] [PUBMED:21518926] [PUBMED:18850010] [PUBMED:19075677] [PUBMED:18457914] [PUBMED:12527906] [PUBMED:15644444] [PUBMED:10784387] [PUBMED:17024155] [PUBMED:19075268] [PUBMED:15826834] [PUBMED:21849159] [PUBMED:21123453] [PUBMED:20974671] [PUBMED:20863376]