full name
aldehyde dehydrogenase 7 family member A1

synonyms
ATQ1, EPD, PDE, ALDH7A1, ENSG00000164904

HGNC
HGNC:877

Entrez Gene
Gene:501

ENSEMBL
ENSG00000164904

location
chr: 5
start: 125877533
stop: 125931104
strand: -

OMIM
OMIM:107323: ALDH7A1 (Autosomal recessive inheritance)
OMIM:266100: Epilepsy, pyridoxine-dependent

transcripts
NM_001202404.1
NM_001182.4
NM_001201377.1

pathways
Arginine and proline metabolism [NCBI:82957] [KEGG:hsa00330] [PUBMED:15590624] [PUBMED:5288244] [PUBMED:16499623]
Ascorbate and aldarate metabolism [NCBI:82932] [KEGG:hsa00053] [PUBMED:16595667] [PUBMED:12644495] [PUBMED:10517845] [PUBMED:17462988] [PUBMED:15564123] [PUBMED:17222174] [PUBMED:14996803]
Biosynthesis of amino acids [NCBI:790012] [KEGG:hsa01230]
Choline catabolism [NCBI:1383062] [REACTOME:R-HSA-6798163] [PUBMED:22483274] [PUBMED:20446114]
Fatty acid degradation [NCBI:82935] [KEGG:hsa00071] [PUBMED:869535]
GABA biosynthesis, eukaryotes, putrescine => GABA [NCBI:413399] [KEGG:hsa_M00135]
Glycerolipid metabolism [NCBI:82986] [KEGG:hsa00561] [PUBMED:11294844] [PUBMED:8662716] [PUBMED:8995384]
Glycerophospholipid biosynthesis [NCBI:1270054] [REACTOME:R-HSA-1483206] [PUBMED:21220505] [PUBMED:19703651] [PUBMED:20823909] [PUBMED:21683693] [PUBMED:21382416] [PUBMED:21704024]
Glycine, serine and threonine metabolism [NCBI:82949] [KEGG:hsa00260] [PUBMED:7639721] [PUBMED:15520012] [PUBMED:11823218] [PUBMED:15470257] [PUBMED:10473374] [PUBMED:16707670] [PUBMED:17636255] [PUBMED:11341914]
Glycolysis / Gluconeogenesis [NCBI:82926] [KEGG:hsa00010]
Histidine metabolism [NCBI:82958] [KEGG:hsa00340]
Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism [NCBI:1309221] [REACTOME:R-HSA-6788656]
Lysine biosynthesis [NCBI:82955] [KEGG:hsa00300] [PUBMED:21550296] [PUBMED:10613839] [PUBMED:14627808] [PUBMED:19620981] [PUBMED:10850974] [PUBMED:12355264] [PUBMED:15160885] [PUBMED:16361515] [PUBMED:15256574] [PUBMED:10074354] [PUBMED:12126930] [PUBMED:21547300] [PUBMED:10714900] [PUBMED:12963379]
Lysine catabolism [NCBI:1270163] [REACTOME:R-HSA-71064] [PUBMED:6434529] [PUBMED:12126930]
Lysine degradation [NCBI:82956] [KEGG:hsa00310] [PUBMED:11802770] [PUBMED:1682209]
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [NCBI:413352] [KEGG:hsa_M00032]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of amino acids and derivatives [NCBI:1270158] [REACTOME:R-HSA-71291]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Phospholipid metabolism [NCBI:1270053] [REACTOME:R-HSA-1483257] [PUBMED:9242906]
Pyruvate metabolism [NCBI:82998] [KEGG:hsa00620] [NCBI:1270123] [REACTOME:R-HSA-70268] [PUBMED:2188967] [PUBMED:7273846]
Tryptophan metabolism [NCBI:82964] [KEGG:hsa00380] [PUBMED:15749753]
Valine, leucine and isoleucine degradation [NCBI:82952] [KEGG:hsa00280]
beta-Alanine metabolism [NCBI:82966] [KEGG:hsa00410]
choline degradation [NCBI:142299] [BIOCYC:HUMAN_CHOLINE-BETAINE-ANA-PWY] [PUBMED:19752176] [PUBMED:6797435] [PUBMED:20207735] [PUBMED:20346934] [PUBMED:22041500] [PUBMED:23906661]
lysine degradation I (saccharopine pathway) [NCBI:142362] [BIOCYC:HUMAN_LYSINE-DEG1-PWY] [PUBMED:24043460] [PUBMED:10775527] [PUBMED:23141293] [PUBMED:19932104] [PUBMED:16491085] [PUBMED:22249334] [PUBMED:11477096]
lysine degradation II (pipecolate pathway) [NCBI:1108775] [BIOCYC:HUMAN_PWY66-425] [PUBMED:24431009] [PUBMED:14235341] [PUBMED:21332720] [PUBMED:4293394] [PUBMED:10642506] [PUBMED:19029248] [PUBMED:24043460]
superpathway of choline degradation to L-serine [NCBI:1108777] [BIOCYC:HUMAN_PWY66-414] [PUBMED:23906661] [PUBMED:10767172] [PUBMED:6797435] [PUBMED:8798461] [PUBMED:20207735] [PUBMED:11231903] [PUBMED:6180732] [PUBMED:19752176] [PUBMED:20346934] [PUBMED:22041500] [PUBMED:8999870]