description
Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which sometimes contains operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003]

external resources
NCBI:82926
KEGG:hsa00010

genes
ADH1A , ADH1B , ADH1C , ADH4 , ADH5 , ADH6 , ADH7 , ALDH2 , ALDH3A1 , ALDH1B1 , ALDH1A3 , ALDH3B1 , ALDH3B2 , ALDH9A1 , ALDH3A2 , ALDOA , ALDOB , ALDOC , ALDH7A1 , BPGM , DLAT , DLD , ENO1 , ENO2 , ENO3 , FBP1 , G6PC , GAPDH , GCK , GPI , HK1 , HK2 , HK3 , LDHA , LDHB , LDHC , PCK1 , PCK2 , PDHA1 , PDHA2 , PDHB , PFKL , PFKM , PFKP , PGAM1 , PGAM2 , PGK1 , PGK2 , PGM1 , PKLR , PKM , TPI1 , FBP2 , MINPP1 , AKR1A1 , GAPDHS , PGM2 , ACSS2 , G6PC2 , HKDC1 , ADPGK , ACSS1 , LDHAL6B , G6PC3 , GALM , LDHAL6A , PGAM4 ,