description
Repetitive presynaptic activity causes long lasting changes in the postsynaptic transmission by changing the type and the number of AMPA receptors. These changes are brought about by trafficking mechanisms that are mainly controlled by activity dependent phosphorylation/desphosphorylation of the GluR1/GluR2 subunits
external resources
NCBI:1268795
REACTOME:R-HSA-399719
PUBMED:19217372
genes
AP2A1
,
AP2A2
,
AP2B1
,
CAMK2A
,
CAMK2B
,
CAMK2D
,
CAMK2G
,
AP2M1
,
AP2S1
,
DLG1
,
DLG4
,
EPB41L1
,
GRIA1
,
GRIA2
,
GRIA3
,
GRIA4
,
MDM2
,
MYO6
,
NSF
,
PRKCA
,
PRKCB
,
PRKCG
,
TSPAN7
,
PICK1
,
AKAP5
,
CACNG3
,
CACNG2
,
GRIP1
,
CACNG4
,
CACNG8
,
GRIP2
,
MIR935
,
