description
Transient increase in intracellular Ca2+ concentration after NMDA receptor activation leads to the activation of the CaMKIV via the activation of CaM-kinase kinase. CaM-kinase kinase and CaMKIV are both activated upon binding Ca2+/Calmodulin after Ca2+ influx through activated NMDA receptor

external resources
NCBI:1268806
REACTOME:R-HSA-442717
PUBMED:18817731

genes
CALM1 , CALM2 , CALM3 , CAMK4 , CREB1 , CAMKK1 ,