description
GABA B receptors are G protein coupled receptors that are activated by GABA binding to the B1 subunit and B2 subunit alters the activity of adenylate cyclase by interacting with the G alpha i/alpha 0 subunit of the pertussis toxin sensitive G protein. The activation of GABA B receptors results in the inhibition of adenylate cyclase activity decreasing the levels of cyclic AMP production and hence the activity of Protein kinase A
external resources
NCBI:1268817
REACTOME:R-HSA-997269
PUBMED:8327893
genes
ADCY1
,
ADCY2
,
ADCY3
,
ADCY5
,
ADCY6
,
ADCY7
,
ADCY8
,
ADCY9
,
GNAI1
,
GNAI2
,
GNAI3
,
GNAL
,
ADCY4
,
GNAT3
,
MIR197
,
