description
Inwardly rectifying K+ channels (Kir channels) show an inward rather than outward (like the voltage gated K+ channels) flow of K+ thereby contributing to maintenance of resting membrane potential and regulation of action potential in excitable tissue. Kir channels are found in a variety of cell types such as cardiac myocytes, neurons, blood cells, osteoblasts, glial cells, epithelial cells, and oocytes. Kir channels can be functionally divided into ATP sensitive K+ channels (Kir 6.1 and Kir 6.2), classical kir channels (Kir 2.1, 2.2, 2.3, 2.4, 5.1) G protein gated K+ channels (Kir 3.1, 3.2, 3.3, 3.4) and K+ transport channels (Kir1.1, 7.1, 4.2, 4.1)

external resources
NCBI:1268824
REACTOME:R-HSA-1296065
PUBMED:20086079
PUBMED:18087715
PUBMED:18691387

genes
GABBR1 , GNB1 , GNB2 , GNB3 , GNG3 , GNG4 , GNG5 , GNG7 , GNG10 , GNGT1 , GNGT2 , KCNJ1 , KCNJ2 , KCNJ3 , KCNJ4 , KCNJ5 , KCNJ6 , KCNJ8 , KCNJ9 , KCNJ10 , KCNJ11 , KCNJ12 , KCNJ14 , KCNJ15 , KCNJ16 , ABCC8 , GABBR2 , ABCC9 , GNG2 , GNG12 , GNG8 ,