description
Activation of Kir 3 channels occurs after binding of G beta gamma subunits of GPCR. Activation of Kir3/GIRK leads to K+ efflux. The dissociation of GPCR into G alpha and G beta gamma subunits is activated by the activation of GABA B receptor by GABA binding

external resources
NCBI:1268826
REACTOME:R-HSA-1296041
PUBMED:20655490

genes
GABBR1 , GNB1 , GNB2 , GNB3 , GNG3 , GNG4 , GNG5 , GNG7 , GNG10 , GNGT1 , GNGT2 , KCNJ2 , KCNJ3 , KCNJ4 , KCNJ5 , KCNJ6 , KCNJ9 , KCNJ10 , KCNJ12 , KCNJ15 , KCNJ16 , GABBR2 , GNG2 , GNG12 , GNG8 ,