description
TREK1 and TREK 2 are activated by physiochemical changes like stretch, convex deformation of the plasma membrane, depolarization, heat and intracellular acidosis. Polyunsaturated fatty acids (PUFA) including arachidonic acid open TREK channels

external resources
NCBI:1268833
REACTOME:R-HSA-1299503
PUBMED:19840997

genes
KCNK2 , KCNK4 , KCNK10 ,