description
Cell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, embryogenesis, and development of neuronal tissue. There are four main groups: the integrin family, the immunoglobulin superfamily, selectins, and cadherins. Membrane proteins that mediate immune cell–cell interactions fall into different categories, namely those involved in antigen recognition, costimulation and cellular adhesion. Furthermore cell-cell adhesions are important for brain morphology and highly coordinated brain functions such as memory and learning. During early development of the nervous system, neurons elongate their axons towards their targets and establish and maintain synapses through formation of cell-cell adhesions. Cell-cell adhesions also underpin axon-axon contacts and link neurons with supporting schwann cells and oligodendrocytes

external resources
NCBI:83069
KEGG:hsa04514
PUBMED:15923648
PUBMED:12500939
PUBMED:15056568
PUBMED:14519386
PUBMED:12234363
PUBMED:10964748
PUBMED:15071551
PUBMED:15551862
PUBMED:14690046
PUBMED:9150551
PUBMED:14519398
PUBMED:14556710
PUBMED:11860281
PUBMED:10664064
PUBMED:9597126
PUBMED:11050419
PUBMED:12367625
PUBMED:10798271
PUBMED:16034094
PUBMED:15115723
PUBMED:15728677
PUBMED:11910893
PUBMED:15561584
PUBMED:15882774
PUBMED:12810109

genes
ALCAM , CD2 , CD4 , CD6 , CD8A , CD8B , CD22 , CD28 , CD80 , CD86 , CD34 , CD40 , CD40LG , CD58 , CDH1 , CDH2 , CDH3 , CDH4 , CDH5 , CDH15 , CNTN1 , CLDN4 , CLDN3 , CLDN7 , VCAN , CTLA4 , GLG1 , HLA-A , HLA-B , HLA-C , HLA-DMA , HLA-DMB , HLA-DOA , HLA-DOB , HLA-DPA1 , HLA-DPB1 , HLA-DQA1 , HLA-DQA2 , HLA-DQB1 , HLA-DRA , HLA-DRB1 , HLA-DRB5 , HLA-E , HLA-F , HLA-G , ICAM1 , ICAM2 , ICAM3 , ITGA6 , ITGA4 , ITGA9 , ITGAL , ITGAM , ITGAV , ITGB1 , ITGB2 , ITGB7 , ITGB8 , L1CAM , MAG , CD99 , MPZ , NCAM1 , NCAM2 , NEO1 , NRCAM , CLDN11 , PDCD1 , PECAM1 , PTPRC , PTPRF , PTPRM , PVR , NECTIN1 , NECTIN2 , SDC1 , SDC2 , SDC4 , SELE , SELL , SELP , SELPLG , SIGLEC1 , SPN , CNTN2 , CLDN5 , VCAM1 , MADCAM1 , CNTNAP1 , ITGA8 , MPZL1 , CLDN10 , CLDN8 , CLDN6 , CLDN2 , CLDN1 , CLDN9 , NRXN3 , NRXN1 , NRXN2 , SDC3 , CD226 , CLDN16 , NLGN4Y , NTNG1 , NLGN1 , NFASC , ICOSLG , CLDN14 , CADM1 , CLDN15 , NECTIN3 , CNTNAP2 , CLDN17 , CD274 , ICOS , CLDN20 , F11R , CLDN18 , CLDN22 , NLGN3 , NLGN4X , NLGN2 , LRRC4C , CADM3 , JAM2 , LRRC4 , VTCN1 , PDCD1LG2 , CD276 , JAM3 , NTNG2 , ESAM , LRRC4B , CLDN23 , CLDN19 , TIGIT , NEGR1 , CLDN25 , CLDN24 , OCLN ,