description
Blood-cell development progresses from a hematopoietic stem cell (HSC), which can undergo either self-renewal or differentiation into a multilineage committed progenitor cell: a common lymphoid progenitor (CLP) or a common myeloid progenitor (CMP). A CLP gives rise to the lymphoid lineage of white blood cells or leukocytes-the natural killer (NK) cells and the T and B lymphocytes. A CMP gives rise to the myeloid lineage, which comprises the rest of the leukocytes, the erythrocytes (red blood cells), and the megakaryocytes that produce platelets important in blood clotting. Cells undergoing these differentiation process express a stage- and lineage-specific set of surface markers. Therefore cellular stages are identified by the specific expression patterns of these genes

external resources
NCBI:83078
KEGG:hsa04640
PUBMED:15629410
PUBMED:15738953
PUBMED:11905810
PUBMED:15156179
PUBMED:12415312
PUBMED:14985712
PUBMED:9927518
PUBMED:15771582
PUBMED:14670296
PUBMED:12360214

genes
ANPEP , CD1A , CD1B , CD1C , CD1D , CD1E , CD2 , CD3D , CD3E , CD3G , CD4 , CD5 , CD7 , CD8A , CD8B , CD9 , CD14 , CD19 , MS4A1 , CD22 , CD33 , CD34 , CD36 , CD37 , CD38 , CD44 , CD59 , CR1 , CR2 , CSF1 , CSF1R , CSF2 , CSF2RA , CSF3 , CSF3R , CD55 , DNTT , EPO , EPOR , FCER2 , FCGR1A , FLT3 , FLT3LG , GP1BA , GP1BB , GP5 , GP9 , GYPA , HLA-DMA , HLA-DMB , HLA-DOA , HLA-DOB , HLA-DPA1 , HLA-DPB1 , HLA-DQA1 , HLA-DQA2 , HLA-DQB1 , HLA-DRA , HLA-DRB1 , HLA-DRB5 , IL1A , IL1B , IL1R1 , IL2RA , IL3 , IL3RA , IL4 , IL4R , IL5 , IL5RA , IL6 , IL6R , IL7 , IL7R , IL9R , IL11 , IL11RA , ITGA6 , ITGA1 , ITGA2 , ITGA2B , ITGA3 , ITGA4 , ITGA5 , ITGAM , ITGB3 , KIT , KITLG , MME , TFRC , THPO , TNF , IL1R2 ,