description
The viral RNP complex is exported from the nucleus via the host cell CRM1 export pathway (Fukuda, 1997; Neumann, 2000; reviewed in Buolo, 2006). The vRNP complex does not interact directly with CRM1 to form an export complex. Rather, an additional viral protein, nuclear export protein (NEP/NS2), acts as an adaptor, binding the viral matrix M1 protein and CRM1, thus linking the viral RNP with CRM1 (Martin, 1991; O'Neill, 1998; Neumann, 2000; Akarsu, 2003). The CRM1/exportin-1 complex recruits additional host cell proteins, and traverses the nuclear pore into the cytosol

external resources
NCBI:1269123
REACTOME:R-HSA-168333
PUBMED:17081640
PUBMED:11118210
PUBMED:12970177

genes
NUP88 , NUP98 , RAN , RANBP2 , TPR , XPO1 , NUP214 , AAAS , RAE1 , NUP155 , NUP93 , NUP58 , POM121 , NUP153 , NUP50 , NUPL2 , NUP205 , NUP210 , NUP160 , NUP188 , NUP62 , NUP54 , NDC1 , NUP133 , NUP107 , NUP37 , NUP85 , SEH1L , NUP35 , NUP43 , POM121C ,