description
The tethering of platelets to the site of vascular injury is the first step in the formation of a platelet thrombus. Firm adhesion of these tethered platelets, as well as the additional recruitment of others onto their surface leads to the formation of large platelet aggregates. The formation of a thrombus is strictly dependent on the formation of interplatelet bonds

external resources
NCBI:1269358
REACTOME:R-HSA-76009
PUBMED:18174460
PUBMED:17585075

genes
ADRA2A , ADRA2B , ADRA2C , AKT1 , CRK , CSK , F2 , FGA , FGB , FGG , FN1 , GP1BA , GP1BB , GP5 , GP9 , GRB2 , ITGA2B , ITGB3 , MPL , PDPK1 , PTK2 , PTPN1 , RAP1A , RAP1B , SHC1 , SOS1 , SRC , SYK , THPO , TLN1 , VWF , BCAR1 , RASGRP1 , RASGRP2 , RAPGEF3 , RAPGEF4 , APBB1IP ,