description
The tethering of platelets to the site of vascular injury is the first step in the formation of a platelet thrombus. Firm adhesion of these tethered platelets, as well as the additional recruitment of others onto their surface leads to the formation of large platelet aggregates. The formation of a thrombus is strictly dependent on the formation of interplatelet bonds
external resources
NCBI:1269358
REACTOME:R-HSA-76009
PUBMED:18174460
PUBMED:17585075
genes
ADRA2A
,
ADRA2B
,
ADRA2C
,
AKT1
,
CRK
,
CSK
,
F2
,
FGA
,
FGB
,
FGG
,
FN1
,
GP1BA
,
GP1BB
,
GP5
,
GP9
,
GRB2
,
ITGA2B
,
ITGB3
,
MPL
,
PDPK1
,
PTK2
,
PTPN1
,
RAP1A
,
RAP1B
,
SHC1
,
SOS1
,
SRC
,
SYK
,
THPO
,
TLN1
,
VWF
,
BCAR1
,
RASGRP1
,
RASGRP2
,
RAPGEF3
,
RAPGEF4
,
APBB1IP
,
