description
Rhodopsin-like receptors (class A/1) are the largest group of GPCRs and are the best studied group from a functional and structural point of view. They show great diversity at the sequence level and thus, can be subdivided into 19 subfamilies (Subfamily A1-19) based on a phylogenetic analysis (Joost P and Methner A, 2002). They represent members which include hormone, light and neurotransmitter receptors and encompass a wide range of functions including many autocrine, paracrine and endocrine processes

external resources
NCBI:1269545
REACTOME:R-HSA-373076
PUBMED:16902930

genes
ADORA1 , ADORA2A , ADORA2B , ADORA3 , ADRA1D , ADRA1B , ADRA1A , ADRA2A , ADRA2B , ADRA2C , ADRB1 , ADRB2 , ADRB3 , AGT , AGTR1 , AGTR2 , APLNR , ANXA1 , APP , AVP , AVPR1A , AVPR1B , AVPR2 , OPN1SW , BDKRB1 , BDKRB2 , CXCR5 , BRS3 , C3 , C3AR1 , C5 , C5AR1 , CCK , CCKAR , CCKBR , CGA , CHRM1 , CHRM2 , CHRM3 , CHRM4 , CHRM5 , CCR1 , CCR3 , CCR4 , CCR5 , CCR6 , CCR7 , CCR8 , LTB4R , CNR1 , CNR2 , CORT , CX3CR1 , DRD1 , DRD2 , DRD3 , DRD4 , DRD5 , GPR183 , ECE1 , S1PR1 , LPAR1 , S1PR3 , EDN1 , EDN2 , EDN3 , EDNRA , EDNRB , F2 , F2R , F2RL1 , F2RL2 , FPR1 , FPR2 , FPR3 , FSHB , FSHR , ACKR1 , GALR1 , OPN1MW , GHSR , GNRH1 , GNRH2 , GNRHR , CCR10 , GPR4 , XCR1 , NPBWR1 , NPBWR2 , CXCR3 , PRLHR , UTS2R , GPR17 , GPR18 , LPAR4 , MCHR1 , GPER1 , GPR31 , GPR35 , GPR37 , MLNR , GPR39 , FFAR1 , FFAR3 , FFAR2 , CXCL1 , CXCL2 , CXCL3 , GRP , GRPR , HCRT , HCRTR1 , HCRTR2 , HRH1 , HRH2 , HTR1A , HTR1B , HTR1D , HTR1E , HTR1F , HTR2A , HTR2B , HTR2C , HTR4 , HTR5A , HTR6 , HTR7 , CXCL8 , CXCR1 , CXCR2 , CXCL10 , INSL3 , KEL , KISS1 , KNG1 , LHB , LHCGR , MC1R , MC2R , MC3R , MC4R , MC5R , CXCL9 , MLN , MTNR1A , MTNR1B , NMB , NMBR , NPY , NPY1R , NPY2R , NPY5R , NTS , NTSR1 , GPR143 , OPRD1 , OPRK1 , OPRL1 , OPRM1 , OXT , OXTR , P2RY1 , P2RY2 , P2RY4 , P2RY6 , P2RY11 , PDYN , PENK , PF4 , PMCH , PNOC , POMC , PPBP , PPY , NPY4R , PSAP , PYY , PTAFR , PTGDR , PTGER1 , PTGER2 , PTGER3 , PTGER4 , PTGFR , PTGIR , OPN1LW , RGR , RHO , RLN2 , SAA1 , CCL1 , CCL5 , CCL13 , CCL16 , CCL19 , CCL20 , CCL21 , CCL23 , CCL25 , CXCL6 , CXCL11 , CXCL5 , XCL1 , CX3CL1 , CXCL12 , SST , SSTR1 , SSTR2 , SSTR3 , SSTR4 , SSTR5 , XCL2 , TAC1 , TACR2 , TAC3 , TACR1 , TACR3 , TBXA2R , TRH , TRHR , TSHB , TSHR , XK , CXCR4 , GPR68 , GPR65 , GALR3 , NPFF , S1PR4 , GALR2 , HCAR3 , APLN , F2RL3 , CCRL2 , TAAR5 , LPAR2 , GPR37L1 , TAAR2 , TAAR3P , GPR55 , S1PR2 , ECE2 , PLPPR4 , P2RY14 , INSL5 , LPAR6 , NMUR1 , CXCL13 , CXCR6 , RRH , CYSLTR1 , CCR9 , CCL27 , NMU , NPFFR2 , PROKR1 , UTS2 , PTGDR2 , HRH3 , LPAR3 , OPN3 , NTSR2 , HCAR1 , OXGR1 , C5AR2 , P2RY10 , GPR132 , HEBP1 , PRLH , GAL , RXFP3 , ACKR4 , GHRL , S1PR5 , P2RY13 , PLPPR1 , LTB4R2 , CCL28 , SUCNR1 , NMUR2 , ACKR3 , CYSLTR2 , LPAR5 , NLN , CXCL16 , HRH4 , RXFP1 , PROK2 , NPFFR1 , PLPPR2 , P2RY12 , PLPPR3 , TAAR8 , QRFPR , PROK1 , MCHR2 , KISS1R , OPN4 , GNRHR2 , RLN3 , RXFP2 , GPHB5 , PROKR2 , NMS , TAAR9 , TAAR1 , GPBAR1 , PLPPR5 , OXER1 , GPHA2 , OPN5 , NPB , UTS2B , NPW , TAAR6 , HCAR2 , FFAR4 , RXFP4 , QRFP , NPSR1 , NPS , CCR2 ,