description
The class A (rhodopsin-like) GPCRs that bind to classical biogenic amine ligands are annotated here. The amines involved (acetylcholine, adrenaline, noradrenaline, dopamine, serotonin and histamine) can all act as neurotransmitters in humans. The so-called 'trace amines', used when referring to p-tyramine, beta-phenylethylamine, tryptamine and octopamine, can also bind to recently-discovered GPCRs

external resources
NCBI:1269553
REACTOME:R-HSA-375280
PUBMED:9311023
PUBMED:11459929
PUBMED:17897004
PUBMED:17073660
PUBMED:7938162
PUBMED:15148138

genes
ADRA1D , ADRA1B , ADRA1A , ADRA2A , ADRA2B , ADRA2C , ADRB1 , ADRB2 , ADRB3 , CHRM1 , CHRM2 , CHRM3 , CHRM4 , CHRM5 , DRD1 , DRD2 , DRD3 , DRD4 , DRD5 , HRH1 , HRH2 , HTR1A , HTR1B , HTR1D , HTR1E , HTR1F , HTR2A , HTR2B , HTR2C , HTR4 , HTR5A , HTR6 , HTR7 , GPR143 , TAAR5 , TAAR2 , TAAR3P , HRH3 , HRH4 , TAAR8 , TAAR9 , TAAR1 , TAAR6 ,