description
This family is known as Family B (secretin-receptor family, family 2) G-protein-coupled receptors. Family B GPCRs include secretin, calcitonin, parathyroid hormone/parathyroid hormone-related peptides and vasoactive intestinal peptide receptors; all of which activate adenylyl cyclase and the phosphatidyl-inositol-calcium pathway (Harmar AJ, 2001)

external resources
NCBI:1269570
REACTOME:R-HSA-373080
PUBMED:11790261

genes
ADCYAP1 , ADCYAP1R1 , ADM , CALCA , CALCB , CALCR , ADGRE5 , CRH , CRHBP , CRHR1 , CRHR2 , CD55 , ADGRE1 , FZD2 , GCG , GCGR , GHRH , GHRHR , GIP , GIPR , GLP1R , GNAS , GNB1 , GNB2 , GNB3 , GNG3 , GNG4 , GNG5 , GNG7 , GNG10 , GNG11 , GNGT1 , GNGT2 , IAPP , IHH , PTCH1 , PTH , PTHLH , PTH1R , PTH2R , SCT , SCTR , SHH , SMO , UCN , WNT1 , WNT2 , WNT3 , WNT5A , WNT6 , WNT7A , WNT7B , WNT8A , WNT8B , WNT10B , WNT11 , WNT2B , WNT9A , WNT9B , FZD5 , FZD3 , FZD1 , FZD4 , FZD6 , FZD7 , FZD8 , FZD9 , PTCH2 , GLP2R , CALCRL , RAMP2 , RAMP1 , RAMP3 , GNB5 , FZD10 , ADGRE2 , DHH , WNT16 , GNG13 , GNG2 , WNT4 , GNG12 , GNB4 , ADM2 , WNT10A , ADGRE3 , WNT3A , UCN2 , GNG8 , PTH2 , UCN3 , MIR4683 ,