description
This family is known as Family B (secretin-receptor family, family 2) G-protein-coupled receptors. Family B GPCRs include secretin, calcitonin, parathyroid hormone/parathyroid hormone-related peptides and vasoactive intestinal peptide receptors; all of which activate adenylyl cyclase and the phosphatidyl-inositol-calcium pathway (Harmar AJ, 2001)
external resources
NCBI:1269570
REACTOME:R-HSA-373080
PUBMED:11790261
genes
ADCYAP1
,
ADCYAP1R1
,
ADM
,
CALCA
,
CALCB
,
CALCR
,
ADGRE5
,
CRH
,
CRHBP
,
CRHR1
,
CRHR2
,
CD55
,
ADGRE1
,
FZD2
,
GCG
,
GCGR
,
GHRH
,
GHRHR
,
GIP
,
GIPR
,
GLP1R
,
GNAS
,
GNB1
,
GNB2
,
GNB3
,
GNG3
,
GNG4
,
GNG5
,
GNG7
,
GNG10
,
GNG11
,
GNGT1
,
GNGT2
,
IAPP
,
IHH
,
PTCH1
,
PTH
,
PTHLH
,
PTH1R
,
PTH2R
,
SCT
,
SCTR
,
SHH
,
SMO
,
UCN
,
WNT1
,
WNT2
,
WNT3
,
WNT5A
,
WNT6
,
WNT7A
,
WNT7B
,
WNT8A
,
WNT8B
,
WNT10B
,
WNT11
,
WNT2B
,
WNT9A
,
WNT9B
,
FZD5
,
FZD3
,
FZD1
,
FZD4
,
FZD6
,
FZD7
,
FZD8
,
FZD9
,
PTCH2
,
GLP2R
,
CALCRL
,
RAMP2
,
RAMP1
,
RAMP3
,
GNB5
,
FZD10
,
ADGRE2
,
DHH
,
WNT16
,
GNG13
,
GNG2
,
WNT4
,
GNG12
,
GNB4
,
ADM2
,
WNT10A
,
ADGRE3
,
WNT3A
,
UCN2
,
GNG8
,
PTH2
,
UCN3
,
MIR4683
,
