description
The classical role of the G-protein beta/gamma dimer was believed to be the inactivation of the alpha subunit, Gbeta/gamma was viewed as a negative regulator of Galpha signalling. It is now known that Gbeta/gamma subunits can directly modulate many effectors, including some also regulated by G alpha

external resources
NCBI:1269580
REACTOME:R-HSA-397795
PUBMED:18834311

genes
AKT1 , AKT2 , RHOA , CSF2 , CSF2RA , CSF2RB , GNB1 , GNB2 , GNB3 , GNG3 , GNG4 , GNG5 , GNG7 , GNG10 , GNG11 , GNGT1 , GNGT2 , GRB2 , IL2 , IL2RA , IL2RB , IL2RG , IL3 , IL3RA , IL5 , IL5RA , JAK1 , JAK2 , JAK3 , PDPK1 , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R2 , PLCB2 , PLCB3 , SHC1 , PIK3R3 , GAB2 , AKT3 , GNB5 , PLCB1 , PIK3R5 , GNG13 , GNG2 , GNG12 , GNB4 , GNG8 , PIK3R6 ,