description
PI3K gamma (PI3KG) is a heterodimer consisting of a p110 catalytic subunit associated with a regulatory p101 or p84 subunit. PI3KG is most highly expressed in neutrophils, where the p101 form predominates (approximately 95%). G beta:gamma recruits PI3KG to the plasma membrane, both activating PI3KG and providing access to its substrate PIP2, which is converted to PIP3

external resources
NCBI:1269581
REACTOME:R-HSA-392451
PUBMED:17916723
PUBMED:17041586

genes
AKT1 , AKT2 , RHOA , CSF2 , CSF2RA , CSF2RB , GNB1 , GNB2 , GNB3 , GNG3 , GNG4 , GNG5 , GNG7 , GNG10 , GNG11 , GNGT1 , GNGT2 , GRB2 , IL2 , IL2RA , IL2RB , IL2RG , IL3 , IL3RA , IL5 , IL5RA , JAK1 , JAK2 , JAK3 , PDPK1 , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R2 , SHC1 , PIK3R3 , GAB2 , AKT3 , GNB5 , PIK3R5 , GNG13 , GNG2 , GNG12 , GNB4 , GNG8 , PIK3R6 ,