description
WNT5A induces internalization of FZD4 in a manner that depends upon PKC-mediated phosphorylation of DVL2. Uptake of FZD4 appears to occur in a clathrin, AP-2 and ARBB2-dependent mannner (Chen et al, 2003; Yu et al, 2007; Yu et al, 2010)
external resources
NCBI:1269613
REACTOME:R-HSA-5099900
PUBMED:12958364
PUBMED:20947020
PUBMED:17199046
genes
AP2A1
,
AP2A2
,
AP2B1
,
ARRB2
,
AP2M1
,
AP2S1
,
CLTA
,
CLTB
,
CLTC
,
DVL2
,
PRKCA
,
PRKCB
,
PRKCG
,
WNT5A
,
FZD4
,
