description
The activity of the upstream binding factor (UBF-1) plays an important role in the regulation of rRNA synthesis. Studies reveal that phosphorylation of UBF-1 is required for its interaction with the RNA polymerase I complex, suggesting that phosphorylation of UBF-1 bound to the rDNA promoter during promoter opening modulates the assembly of the transcription initiation complex

external resources
NCBI:1269659
REACTOME:R-HSA-73728

genes
HIST1H2AE , HIST1H2AD , H2AFX , H2AFZ , HIST1H2BD , HIST1H2BB , H3F3A , H3F3B , MAPK3 , UBTF , HIST1H4I , HIST1H2AJ , HIST1H2AC , HIST1H2AB , HIST2H2AA3 , HIST2H2AC , HIST1H2BG , HIST1H2BL , HIST1H2BN , HIST1H2BM , HIST1H2BF , HIST1H2BE , HIST1H2BH , HIST1H2BI , HIST1H2BC , HIST1H2BO , HIST2H2BE , HIST1H3A , HIST1H3D , HIST1H3C , HIST1H3E , HIST1H3I , HIST1H3G , HIST1H3J , HIST1H3H , HIST1H3B , HIST1H4A , HIST1H4D , HIST1H4F , HIST1H4K , HIST1H4J , HIST1H4C , HIST1H4H , HIST1H4B , HIST1H4E , HIST1H4L , HIST2H4A , MBD2 , HIST1H3F , HIST1H2BJ , H2AFJ , HIST1H2BK , H2AFV , HIST4H4 , HIST2H3C , HIST3H2BB , HIST1H2BA , HIST2H3A , H2AFB1 , HIST2H4B , HIST2H3D , HIST2H2AA4 , MIR4738 ,