description
The type 2 promoters can recruit TFIIIC without the help of TFIIIA because TFIIIC binds directly to the A and B boxes. As for the type 1 promoters, this then allows the binding of Brf1-TFIIIB and RNA polymerase III. Importantly, in the yeast system, once Brf1-TFIIIB has been recruited to type 1 or 2 promoters, TFIIIA and/or TFIIIC can be stripped from the DNA with high salt or heparin treatment. Brf1-TFIIIB remains bound to the DNA and is sufficient to direct multiple rounds of transcription

external resources
NCBI:1269668
REACTOME:R-HSA-76066

genes
POLR3D , BRF1 , GTF3C1 , GTF3C2 , POLR2E , POLR2F , POLR2H , POLR2K , POLR2L , TBP , GTF3C5 , GTF3C4 , GTF3C3 , POLR1C , POLR3F , POLR3G , POLR3C , POLR3A , CRCP , POLR1D , POLR3K , POLR3B , POLR3E , BDP1 , POLR3GL , GTF3C6 , POLR3H ,