description
The degradation of mRNA from 3' to 5' occurs in two steps. First, the exosome exoribonuclease complex binds the 3' end of the oligoadenylated mRNA and hydrolyzes it from 3' to 5', yielding ribonucleotides having 5'-monophosphates, until a capped oligoribonucleotide remains. Second, the scavenging decapping enzyme DCPS hydrolyzes the 7-methylguanosine cap

external resources
NCBI:1269714
REACTOME:R-HSA-429958
PUBMED:14749774
PUBMED:19239894
PUBMED:15475613
PUBMED:16141059
PUBMED:17245413
PUBMED:11283721

genes
EXOSC9 , SKIV2L , TTC37 , HBS1L , EXOSC8 , DIS3 , EXOSC7 , EXOSC2 , DCPS , EXOSC3 , EXOSC1 , EXOSC4 , EXOSC5 , WDR61 , NT5C3B , EXOSC6 ,