description
After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified

external resources
NCBI:125136
KEGG:hsa03040
PUBMED:10978320
PUBMED:19239890
PUBMED:19733268
PUBMED:17537823

genes
CDC5L , DDX5 , DHX8 , DHX15 , HNRNPA1 , HNRNPC , HNRNPK , HNRNPU , HSPA1A , HSPA1B , HSPA1L , HSPA2 , HSPA6 , HSPA8 , MAGOH , HNRNPM , NCBP1 , SNU13 , PCBP1 , PLRG1 , RP9 , SRSF1 , SRSF2 , SRSF3 , SRSF4 , SRSF5 , SRSF6 , SRSF7 , TRA2B , SNRNP70 , SNRPA , SNRPA1 , SNRPB , SNRPB2 , SNRPC , SNRPD1 , SNRPD2 , SNRPD3 , SNRPE , SNRPF , SNRPG , U2AF1 , DDX39B , SF3A2 , DHX16 , PRPF18 , SRSF9 , BUD31 , SART1 , PRPF4 , PRPF3 , EFTUD2 , SNRNP40 , DDX23 , AQR , EIF4A3 , DHX38 , DDX46 , RBM8A , THOC1 , PQBP1 , ALYREF , SF3B4 , SMNDC1 , BCAS2 , SF3A1 , PPIE , PPIH , CHERP , SLU7 , PRPF8 , USP39 , SRSF10 , TXNL4A , TCERG1 , SRSF8 , SF3A3 , SF3B2 , SNRNP27 , LSM6 , DDX42 , U2AF2 , PUF60 , NCBP2 , SNW1 , ACIN1 , SNRNP200 , U2SURP , SF3B3 , SF3B1 , LSM5 , PRPF6 , PRPF40B , LSM4 , SYF2 , PRPF31 , RNU6-1 , LSM3 , RBMXL2 , RBMX , PRPF19 , TRA2A , CRNKL1 , CDC40 , CWC15 , SF3B6 , PPIL1 , LSM7 , LSM8 , WBP11 , MAGOHB , PRPF38B , PRPF40A , RBM22 , CTNNBL1 , XAB2 , THOC2 , ISY1 , LSM2 , RBM25 , SF3B5 , THOC3 , PHF5A , PRPF38A , RBM17 , RBMXL3 , HNRNPA1L2 , CCDC12 , ZMAT2 , U2AF1L4 , HNRNPA3 , RBMXL1 , ISY1-RAB43 ,