description
DNA synthesis occurs in the S phase, or the synthesis phase, of the cell cycle. The cell duplicates its hereditary material, and two copies of the chromosome are formed. As DNA replication continues, the E type cyclins shared by the G1 and S phases, are destroyed and the levels of the mitotic cyclins rise
external resources
NCBI:1269777
REACTOME:R-HSA-69242
genes
CCND1
,
CCNA2
,
CCNE1
,
CCNH
,
CDC6
,
CDC25A
,
CDC25B
,
CDK2
,
CDK4
,
CDK7
,
CDKN1A
,
CDKN1B
,
CKS1B
,
DNA2
,
FEN1
,
LIG1
,
MAX
,
MCM2
,
MCM3
,
MCM4
,
MCM5
,
MCM6
,
MCM7
,
MNAT1
,
MYC
,
ORC1
,
ORC2
,
ORC4
,
ORC5
,
PCNA
,
POLA1
,
POLD1
,
POLD2
,
POLE
,
POLE2
,
PRIM1
,
PSMA1
,
PSMA2
,
PSMA3
,
PSMA4
,
PSMA5
,
PSMA6
,
PSMA7
,
PSMB1
,
PSMB2
,
PSMB3
,
PSMB4
,
PSMB5
,
PSMB6
,
PSMB7
,
PSMB8
,
PSMB9
,
PSMB10
,
PSMC1
,
PSMC2
,
PSMC3
,
PSMC4
,
PSMC5
,
PSMC6
,
PSMD1
,
PSMD2
,
PSMD3
,
PSMD4
,
PSMD5
,
PSMD7
,
PSMD8
,
PSMD9
,
PSMD10
,
PSMD11
,
PSMD12
,
PSMD13
,
PSME1
,
PSME2
,
PTK6
,
RAD21
,
RB1
,
RFC1
,
RFC2
,
RFC3
,
RFC4
,
RFC5
,
RPA1
,
RPA2
,
RPA3
,
RPS27A
,
SKP1
,
SKP2
,
UBA52
,
UBB
,
UBC
,
WEE1
,
SEM1
,
SMC1A
,
CDC45
,
CUL1
,
CCNA1
,
SMC3
,
CCNE2
,
PSMF1
,
GINS1
,
PSMD6
,
PSME3
,
PSMD14
,
STAG1
,
POLD3
,
STAG2
,
PDS5B
,
WAPL
,
PSME4
,
PDS5A
,
ORC6
,
ORC3
,
POLA2
,
FZR1
,
GINS2
,
POLE3
,
POLE4
,
POLD4
,
GINS3
,
CDT1
,
GINS4
,
MCM8
,
CDCA5
,
ESCO1
,
PSMB11
,
PSMA8
,
ESCO2
,
C7orf76
,
MIR3610
,
LOC100506136
,
