description
The actual synthesis of DNA occurs in the S phase of the cell cycle. This includes the initiation of DNA replication, when the first nucleotide of the new strand is laid down during the synthesis of the primer. The DNA replication preinitiation events begin in late M or early G1 phase

external resources
NCBI:1269779
REACTOME:R-HSA-69239

genes
CCNA2 , CDC6 , CDK2 , CDKN1A , CDKN1B , DNA2 , FEN1 , LIG1 , MCM2 , MCM3 , MCM4 , MCM5 , MCM6 , MCM7 , ORC1 , ORC2 , ORC4 , ORC5 , PCNA , POLA1 , POLD1 , POLD2 , POLE , POLE2 , PRIM1 , PSMA1 , PSMA2 , PSMA3 , PSMA4 , PSMA5 , PSMA6 , PSMA7 , PSMB1 , PSMB2 , PSMB3 , PSMB4 , PSMB5 , PSMB6 , PSMB7 , PSMB8 , PSMB9 , PSMB10 , PSMC1 , PSMC2 , PSMC3 , PSMC4 , PSMC5 , PSMC6 , PSMD1 , PSMD2 , PSMD3 , PSMD4 , PSMD5 , PSMD7 , PSMD8 , PSMD9 , PSMD10 , PSMD11 , PSMD12 , PSMD13 , PSME1 , PSME2 , RB1 , RFC1 , RFC2 , RFC3 , RFC4 , RFC5 , RPA1 , RPA2 , RPA3 , RPS27A , UBA52 , UBB , UBC , SEM1 , CDC45 , CCNA1 , PSMF1 , GINS1 , PSMD6 , PSME3 , PSMD14 , POLD3 , PSME4 , ORC6 , ORC3 , POLA2 , FZR1 , GINS2 , POLE3 , POLE4 , POLD4 , GINS3 , CDT1 , GINS4 , MCM8 , PSMB11 , PSMA8 , C7orf76 , LOC100506136 ,