description
The nuclear envelope breakdown (NEBD) happens in late prophase of mitosis and involves disassembly of the nuclear pore complex, depolymerization of the nuclear lamina, and clearance of nuclear envelope from chromatin. NEBD allows mitotic spindle microtubules to access condensed chromosomes at kinetochores and enables nuclear division and segregation of genetic material to two daughter cells. For a recent review, please refer to Guttinger et al. 2009

external resources
NCBI:1269815
REACTOME:R-HSA-2980766
PUBMED:19234477

genes
CCNB1 , CDK1 , EMD , LMNA , LMNB1 , NUP88 , NUP98 , PLK1 , PRKCA , PRKCB , RANBP2 , TMPO , TPR , VRK1 , VRK2 , NUP214 , AAAS , RAE1 , BANF1 , CCNB2 , NUP155 , LPIN2 , NUP93 , NUP58 , POM121 , NUP153 , NUP50 , NEK6 , NUPL2 , NUP205 , LPIN1 , NUP210 , NUP160 , CTDNEP1 , NUP188 , LEMD3 , NUP62 , NUP54 , NDC1 , NUP133 , NUP107 , LPIN3 , NUP37 , NUP85 , SEH1L , NEK9 , NUP35 , NEK7 , LEMD2 , CNEP1R1 , NUP43 , POM121C ,