description
The dissolution of the nuclear membrane marks the beginning of the prometaphase. Kinetochores are created when proteins attach to the centromeres. Microtubules then attach at the kinetochores, and the chromosomes begin to move to the metaphase plate

external resources
NCBI:1269820
REACTOME:R-HSA-68877

genes
BIRC5 , BUB1 , BUB1B , CCNB1 , CDK1 , CDC20 , CENPA , CENPC , CENPE , CENPF , CSNK2A1 , CSNK2A2 , CSNK2B , CENPI , INCENP , KIF2A , MAD2L1 , NUP98 , PAFAH1B1 , PLK1 , PPP1CC , PPP2CA , PPP2CB , PPP2R1A , PPP2R1B , PPP2R5A , PPP2R5B , PPP2R5C , PPP2R5D , PPP2R5E , RAD21 , RANBP2 , RANGAP1 , RPS27 , CLIP1 , SEC13 , XPO1 , SMC1A , MAD1L1 , SMC3 , CCNB2 , ZW10 , BUB3 , AURKB , KNTC1 , CKAP5 , NCAPD2 , SMC4 , STAG1 , NDC80 , SMC2 , NUDC , STAG2 , KIF2C , ZWINT , PMF1 , MAPRE1 , PDS5B , WAPL , CLASP2 , PDS5A , NUP160 , CLASP1 , NCAPH , ITGB3BP , AHCTF1 , NSL1 , NDE1 , ERCC6L , SPDL1 , ZWILCH , CDCA8 , CENPQ , NUP133 , CENPN , HDAC8 , RCC2 , KNL1 , NUP107 , SPC25 , TAOK1 , CENPK , NCAPG , CENPH , MIS12 , CENPM , NUP37 , CENPO , CENPU , NUP85 , DSN1 , CENPT , B9D2 , NDEL1 , SEH1L , KIF18A , NUF2 , KIF2B , CENPL , CDCA5 , SPC24 , SGO2 , SGO1 , SKA1 , SKA2 , NUP43 , CENPS , CENPP , MIR484 , MIR3610 , MIR4523 ,