description
Finally, progression out of mitosis and division of the cell into two daughters (cytokinesis) requires the inactivation of Cyclin B - Cdc2 by ubiquitin-dependent proteolysis of Cyclin A and B, which is regulated by a large E3 ubiquitin ligase complex known as the Anaphase Promoting Complex (APC).The detailed annotation of the M/G1 transition will be completed in a later version of GK

external resources
NCBI:1269831
REACTOME:R-HSA-68874

genes
CDC6 , CDK2 , E2F1 , E2F2 , E2F3 , MCM2 , MCM3 , MCM4 , MCM5 , MCM6 , MCM7 , ORC1 , ORC2 , ORC4 , ORC5 , POLA1 , POLE , POLE2 , PRIM1 , PSMA1 , PSMA2 , PSMA3 , PSMA4 , PSMA5 , PSMA6 , PSMA7 , PSMB1 , PSMB2 , PSMB3 , PSMB4 , PSMB5 , PSMB6 , PSMB7 , PSMB8 , PSMB9 , PSMB10 , PSMC1 , PSMC2 , PSMC3 , PSMC4 , PSMC5 , PSMC6 , PSMD1 , PSMD2 , PSMD3 , PSMD4 , PSMD5 , PSMD7 , PSMD8 , PSMD9 , PSMD10 , PSMD11 , PSMD12 , PSMD13 , PSME1 , PSME2 , RPA1 , RPA2 , RPA3 , RPS27A , UBA52 , UBB , UBC , SEM1 , CDC7 , CDC45 , PSMF1 , PSMD6 , PSME3 , PSMD14 , DBF4 , PSME4 , ORC6 , ORC3 , POLA2 , RPA4 , GMNN , POLE3 , MCM10 , POLE4 , CDT1 , MCM8 , PSMB11 , PSMA8 , C7orf76 , LOC100506136 ,