description
As inferred from mouse, BMAL1:CLOCK (ARNTL:CLOCK) and BMAL1:NPAS2 (ARNTL:NPAS2) heterodimers bind to sequence elements (E boxes) in the promoters of target genes and enhance transcription (Gekakis et al. 1998, reviewed in Munoz and Baler 2003)

external resources
NCBI:1269872
REACTOME:R-HSA-1368108
PUBMED:12868535
PUBMED:9616112

genes
ARNTL , AVP , CREB1 , CREBBP , CREM , CRY1 , CRY2 , DBP , EP300 , F7 , NR3C1 , HIF1A , NFIL3 , NPAS2 , SERPINE1 , PER1 , PPARA , MED1 , RBM4 , RORA , RXRA , SMARCD3 , TBL1X , NRIP1 , BHLHE40 , NCOA1 , HDAC3 , PER2 , NR1D1 , CLOCK , NCOR1 , NAMPT , CARM1 , NCOA2 , PPARGC1A , NCOA6 , CRTC1 , NOCT , KLF15 , ARNTL2 , BHLHE41 , TBL1XR1 , CHD9 , HELZ2 , TGS1 , SIK1 , MIR1281 ,