description
The half-life of Cx is very short (1 to 5h) compared to other junctional proteins (Laird et al., 1995 ; Fallon and Goudenough, 1981). Connexins are targeted for degradation by the proteasome and the lysosome. Degradation appears to involve the phosphorylation of Connexins as well as their interactions with other proteins (Piehl et al., 2007)

external resources
NCBI:1269891
REACTOME:R-HSA-190873
PUBMED:17108328
PUBMED:8522583

genes
AP2M1 , CLTA , CLTB , CLTC , DAB2 , DNM1 , DNM2 , GJA1 , MYO6 , CLTCL1 ,