description
The P-type ATPases (E1-E2 ATPases) are a large group of evolutionarily related ion pumps that are found in bacteria, archaea and eukaryotes. They are referred to as P-type ATPases because they catalyze auto-phosphorylation of a key conserved aspartate residue within the pump. They all appear to interconvert between at least two different conformations, E1 and E2. Most members of this transporter family pump a large variety of cations (Kuhlbrandt W, 2004)
external resources
NCBI:1269951
REACTOME:R-HSA-936837
PUBMED:15071553
genes
ATP1A1
,
ATP1A2
,
ATP1A3
,
ATP12A
,
ATP1A4
,
ATP1B1
,
ATP1B2
,
ATP1B3
,
FXYD2
,
ATP2A1
,
ATP2A2
,
ATP2A3
,
ATP2B1
,
ATP2B2
,
ATP2B3
,
ATP2B4
,
ATP4A
,
ATP4B
,
ATP7A
,
ATP7B
,
CALM1
,
CALM2
,
CALM3
,
CAMK2A
,
CAMK2B
,
CAMK2D
,
CAMK2G
,
ATP8B1
,
FXYD1
,
FXYD3
,
PLN
,
SLN
,
SRI
,
ATP2C2
,
ATP9A
,
ATP8A1
,
ATP10B
,
ATP11B
,
ATP11A
,
ATP13A2
,
ATP2C1
,
CUTC
,
PDZD11
,
ATP8A2
,
FXYD7
,
FXYD6
,
FXYD4
,
ATP13A1
,
ATP10A
,
ATP8B2
,
ATP10D
,
ATP8B4
,
ATP13A4
,
ATP8B3
,
ATP11C
,
ATP13A5
,
ATP9B
,
