Logo
description
Metabolic processes in human cells generate energy through the oxidation of molecules consumed in the diet and mediate the synthesis of diverse essential molecules not taken in the diet as well as the inactivation and elimination of toxic ones generated endogenously or present in the extracellular environment. The processes of energy metabolism can be classified into two groups according to whether they involve carbohydrate-derived or lipid-derived molecules, and within each group it is useful to distinguish processes that mediate the breakdown and oxidation of these molecules to yield energy from ones that mediate their synthesis and storage as internal energy reserves. Synthetic reactions are conveniently grouped by the chemical nature of the end products, such as nucleotides, amino acids and related molecules, and porphyrins. Detoxification reactions (biological oxidations) are likewise conveniently classified by the chemical nature of the toxin.At the same time, all of these processes are tightly integrated. Intermediates in reactions of energy generation are starting materials for biosyntheses of amino acids and other compounds, broad-specificity oxidoreductase enzymes can be involved in both detoxification reactions and biosyntheses, and hormone-mediated signaling processes function to coordinate the operation of energy-generating and energy-storing reactions and to couple these to other biosynthetic processes

external resources
NCBI:1269956
REACTOME:R-HSA-1430728

genes
A2M , NAT1 , NAT2 , AADAC , AANAT , ABCA1 , ABCB7 , AOC1 , ACAA1 , ACACA , ACACB , ACADL , ACADM , ACADS , ACADSB , ACADVL , ACAT1 , ACAT2 , ACHE , ACLY , ACO2 , ACOX1 , ACP5 , ACY1 , ADA , ADCY1 , ADCY2 , ADCY3 , ADCY5 , ADCY6 , ADCY7 , ADCY8 , ADCY9 , PLIN2 , ADH1A , ADH1B , ADH1C , ADH4 , ADH5 , ADH6 , ADH7 , ADK , PARP4 , ADRA2A , ADRA2C , ADSL , ADSS , AP2A1 , AP2A2 , AP2B1 , ACAN , AGL , AGT , AGXT , AHCY , AHR , AK1 , AK2 , AK4 , AKT1 , ALAD , ALAS1 , ALAS2 , ALB , ABCD1 , ALDH1A1 , ALDH2 , ALDH3A1 , ALDH1B1 , ALDH3B1 , ALDH3B2 , ALDH9A1 , ALDH3A2 , ALDOA , ALDOB , ALDOC , AKR1B1 , ALOX12 , ALOX5 , ALOX5AP , ALOX12B , ALOX15 , ALOX15B , ALPI , AMD1 , AMPD1 , AMPD2 , AMPD3 , AMT , AMY1A , AMY1B , AMY1C , AMY2A , AMY2B , SLC25A4 , SLC25A5 , SLC25A6 , AOC2 , AOX1 , APOF , APOA1 , APOA2 , APOA4 , APOB , APOC1 , APOC2 , APOC3 , APOC4 , APOE , APRT , AQP1 , ARF1 , ARF3 , ARG1 , ARG2 , ARL2 , ARNT , ARNTL , ARSA , ARSB , STS , ARSD , ARSE , ARSF , ASAH1 , ASL , ASMT , ASNS , ASPA , ASS1 , ATIC , ATP5F1A , ALDH7A1 , ATP5F1B , ATP5F1C , ATP5F1D , ATP5F1E , ATP5PB , ATP5MC1 , ATP5MC2 , ATP5MC3 , ATP5ME , ATP5PF , ATP5PO , AUH , BAAT , BCAT1 , BCAT2 , BCHE , BCKDHA , BCKDHB , BDH1 , BGN , BHMT , BLVRA , BLVRB , BMP1 , BMX , BPGM , BPHL , BSG , BST1 , BTD , CA1 , CA2 , CA3 , CA4 , CA5A , CA6 , CA7 , CA9 , CA12 , CACNA1A , CACNA1C , CACNA1D , CACNA1E , CACNB2 , CACNB3 , SLC25A20 , CAD , CALM1 , CALM2 , CALM3 , CAT , CAV1 , CBR1 , CBR3 , CBS , KYAT1 , CCNC , CD36 , SCARB1 , CD38 , ENTPD1 , ENTPD2 , ENTPD6 , ENTPD3 , ENTPD5 , CD44 , CDA , CDK8 , CDO1 , CDS1 , CEL , CES1 , CETP , CGA , CHAT , AKR1C4 , CHIT1 , CHKA , CHKB , CHRM3 , CIDEA , CKB , CKM , CKMT1B , CKMT2 , AP2M1 , AP2S1 , CLPS , CLTA , CLTC , COMT , COX4I1 , COX5B , COX6A1 , COX6B1 , COX6C , COX7B , COX7C , COX8A , COX10 , COX11 , COX15 , CPOX , CPS1 , CPT1A , CPT1B , CPT2 , CRAT , CREBBP , CRYM , CS , CSNK1G2 , CSNK2A1 , CSNK2A2 , CSNK2B , VCAN , NCAN , CSPG4 , SLC25A10 , CTGF , CTH , CTPS1 , CTRB1 , CYB5A , CYC1 , CYP1A1 , CYP1A2 , CYP1B1 , CYP2A6 , CYP2A7 , CYP3A7 , CYP2A13 , CYP2B6 , CYP2C19 , CYP2C8 , CYP2C9 , CYP2C18 , CYP2D6 , CYP2E1 , CYP2F1 , CYP2J2 , CYP3A4 , CYP3A5 , CYP4A11 , CYP4B1 , CYP7A1 , CYP8B1 , CYP11A1 , CYP11B1 , CYP11B2 , CYP17A1 , CYP19A1 , CYP21A2 , CYP24A1 , CYP26A1 , CYP27A1 , CYP27B1 , CYP51A1 , DAB1 , DAO , DARS , DBH , DBI , DBT , ECI1 , DCK , DCN , DCTD , DCT , DDC , AKR1C1 , AKR1C2 , DECR1 , DGUOK , DHCR7 , DHCR24 , DHFR , DHODH , CYB5R3 , NQO1 , DIO1 , DIO2 , DIO3 , DLAT , DLD , DLST , SARDH , DNM2 , DPEP1 , DPYD , DPYS , SLC26A2 , DTYMK , DUT , TYMP , ECHS1 , EHHADH , ENO1 , ENO2 , ENO3 , EP300 , EPHX1 , EPHX2 , EPRS , ERCC2 , ESD , ESRRA , ETFA , ETFB , ETFDH , EXT1 , EXT2 , FAAH , FABP4 , FABP1 , FABP2 , FABP3 , FABP5 , FABP6 , FABP7 , ACSL1 , ACSL3 , ACSL4 , FAH , FASN , FAU , FBP1 , FDFT1 , FDPS , FDX1 , FDXR , FECH , GPC4 , GPC5 , FH , FHL2 , FMO1 , FMO2 , FMO3 , FMOD , FOLH1 , FOLR2 , FPGS , FXN , KDSR , FYN , G6PC , G6PD , SLC37A4 , GAA , GALC , GALE , B4GALNT1 , GALK1 , GALT , GAMT , GAPDH , GART , GATM , GBA , GBE1 , GC , GCDH , GCG , GCGR , GCH1 , GCHFR , GCK , GCKR , GCSH , GDF1 , GGT1 , GGT3P , B4GALT1 , GGT7 , GGT5 , GIF , GK , GK2 , GLA , GPC3 , GLB1 , GCLC , GCLM , GLDC , GLO1 , GLP1R , GLS , GLRX , GLUD1 , GLUD2 , GLUL , GM2A , GMPR , GNA11 , GNA15 , GNAI1 , GNAI2 , GNAQ , GNAS , GNB1 , GNB2 , GNB3 , GNG3 , GNG4 , GNG5 , GNG7 , GNG10 , GNG11 , GNGT1 , GNGT2 , GNS , GOT1 , GOT2 , GPC1 , GPD1 , GPD2 , GPI , FFAR1 , GPT , GPX1 , GPX2 , GPX4 , GSR , GSS , GSTA1 , GSTA2 , GSTA3 , GSTA4 , GSTM1 , GSTM2 , GSTM3 , GSTM4 , GSTM5 , GSTP1 , GSTT1 , GSTT2 , GSTZ1 , GUCA2A , GUCA2B , GUCY2C , GUK1 , GUSB , GYG1 , GYS1 , GYS2 , HSD17B10 , HAGH , HADHA , HADHB , HADH , HAL , HAS1 , HAS2 , HAS3 , HBA1 , HBA2 , HBB , HDC , HDLBP , HEXA , HEXB , HGD , HK1 , HK2 , HK3 , HLCS , HMBS , HMGCL , HMGCR , HMGCS1 , HMGCS2 , HMMR , HMOX1 , HMOX2 , HNMT , HPD , HPGD , HPRT1 , HSD3B1 , HSD3B2 , HSD11B1 , HSD11B2 , HSD17B1 , HSD17B3 , HSD17B2 , HSD17B4 , HSP90AA1 , HSP90AB1 , HSPG2 , NDST1 , HYAL1 , IARS , IDH1 , IDH2 , IDH3A , IDH3B , IDH3G , IDI1 , IDS , IDUA , IMPA1 , IMPA2 , IMPDH1 , IMPDH2 , IDO1 , INPP1 , INS , INPP4A , INPP5A , INPP5B , INPP5D , INPPL1 , INSIG1 , ITPA , ITPK1 , ITPKA , ITPKB , ITPR1 , ITPR2 , ITPR3 , IVD , KARS , KCNB1 , KCNC2 , KCNJ11 , KCNS3 , KHK , KPNB1 , LALBA , RPSA , LBR , LCAT , LCT , LDHA , LDHB , LDHC , LDLR , LHB , LIPA , LIPC , LIPE , FADS1 , LPA , LPL , LRP1 , LRP2 , LSS , LTA4H , CYP4F3 , LTC4S , LUM , MARCKS , MAN2C1 , MAN2B1 , MANBA , MAOA , MAOB , MARS , MAT1A , MAT2A , CHST6 , MDH1 , MDH2 , ME1 , MGST1 , MGST2 , MGST3 , ALDH6A1 , MOCS1 , MOCS2 , ABCC1 , MT1A , MT1B , MT1E , MT1F , MT1G , MT1H , MT1M , MT1X , MT2A , MT3 , MTAP , MT-ATP6 , MT-ATP8 , MT-CO1 , MT-CO2 , MT-CO3 , MT-CYB , MTF1 , NUDT1 , MTHFD1 , MTHFR , MTM1 , MT-ND1 , MT-ND2 , MT-ND3 , MT-ND4 , MT-ND5 , MT-ND6 , MTTP , MTR , MTRR , MUT , MVD , MVK , NAGLU , NUBP1 , NDUFA1 , NDUFA2 , NDUFA3 , NDUFA4 , NDUFA5 , NDUFA6 , NDUFA7 , NDUFA8 , NDUFA9 , NDUFA10 , NDUFAB1 , NDUFB1 , NDUFB2 , NDUFB3 , NDUFB4 , NDUFB5 , NDUFB6 , NDUFB7 , NDUFB8 , NDUFB9 , NDUFB10 , NDUFC1 , NDUFC2 , NDUFS1 , NDUFS2 , NDUFS3 , NDUFV1 , NDUFS4 , NDUFS5 , NDUFS6 , NDUFS8 , NDUFV2 , NDUFV3 , RPL10A , NEU1 , NEU2 , NFYA , NFYB , NFYC , NME1 , NME2 , NME4 , NQO2 , NNMT , NOS3 , PNP , NPAS2 , NPC1 , NRF1 , NT5E , NUP88 , NUP98 , OAT , OAZ1 , OAZ2 , OCA2 , OCRL , ODC1 , OMD , OGDH , OGN , OSBP , OTC , OXCT1 , P4HB , FURIN , PCSK6 , PAH , PC , PCBD1 , PCCA , PCCB , PCK1 , PCK2 , PCSK5 , PCYT1A , PDHA1 , PDHB , PDK1 , PDK2 , PDK3 , PDK4 , ENPP1 , ENPP2 , ENPP3 , PFAS , PFKFB1 , PFKFB2 , PFKFB3 , PFKFB4 , PFKL , PFKM , PFKP , PGAM1 , PGAM2 , PGD , PGK1 , PGK2 , PGM1 , ABCB1 , ABCB4 , PHKA1 , PHKA2 , PHKB , PHKG1 , PHKG2 , PHYH , PIK3C2A , PIK3C2B , PIK3C2G , PIK3C3 , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R2 , PI4KA , PI4KB , PIP4K2A , PKLR , PKM , PLA2G1B , PLA2G2A , PLA2G4A , PLA2G5 , PLCB2 , PLCB3 , PLCB4 , PLCD1 , PLCG1 , PLCG2 , PLD1 , PLD2 , PLIN1 , PLTP , PNLIP , PNLIPRP1 , PNLIPRP2 , PNMT , POLD1 , POMC , PON1 , PON2 , PON3 , POR , PPA1 , PPARA , PPARD , PPARG , MED1 , PPAT , CTSA , PPOX , PPP1CA , PPP1CB , PPP1CC , PPP1R3C , PPP2CA , PPP2CB , PPP2R1A , PPP2R1B , PPP2R5D , PPT1 , PRELP , PRKAA2 , PRKAB2 , PRKACA , PRKACB , PRKACG , PRKAR1A , PRKAR1B , PRKAR2A , PRKAR2B , PRKCA , PRKD1 , PRKG2 , PRODH , PRPS1 , PRPS2 , LGMN , PRSS1 , PRSS3 , RELN , PSAP , PSMA1 , PSMA2 , PSMA3 , PSMA4 , PSMA5 , PSMA6 , PSMA7 , PSMB1 , PSMB2 , PSMB3 , PSMB4 , PSMB5 , PSMB6 , PSMB7 , PSMB8 , PSMB9 , PSMB10 , PSMC1 , PSMC2 , PSMC3 , PSMC4 , PSMC5 , PSMC6 , PSMD1 , PSMD2 , PSMD3 , PSMD4 , PSMD5 , PSMD7 , PSMD8 , PSMD9 , PSMD10 , PSMD11 , PSMD12 , PSMD13 , PSME1 , PSME2 , PSPH , PTEN , PTGDS , PTGIS , PTGS1 , PTGS2 , PTPN13 , PTS , ABCD4 , PYCR1 , ALDH18A1 , PCYT2 , PYGB , PYGL , PYGM , QARS , QDPR , RAB4A , RAB5A , RAN , RANBP2 , RAP1A , RARS , RARRES3 , RBP1 , RBP2 , RBP4 , RHAG , RORA , RPE , RPL3 , RPL3L , RPL4 , RPL5 , RPL6 , RPL7 , RPL7A , RPL8 , RPL9 , RPL10 , RPL11 , RPL12 , RPL13 , RPL15 , RPL17 , RPL18 , RPL18A , RPL19 , RPL21 , RPL22 , RPL23A , RPL24 , RPL26 , RPL27 , RPL30 , RPL27A , RPL28 , RPL29 , RPL31 , RPL32 , RPL34 , RPL35A , RPL36AL , RPL37 , RPL37A , RPL38 , RPL39 , RPL41 , RPL36A , RPLP0 , RPLP1 , RPLP2 , RPS2 , RPS3 , RPS3A , RPS4X , RPS4Y1 , RPS5 , RPS6 , RPS7 , RPS8 , RPS9 , RPS10 , RPS11 , RPS12 , RPS13 , RPS14 , RPS15 , RPS15A , RPS16 , RPS17 , RPS18 , RPS19 , RPS20 , RPS21 , RPS23 , RPS24 , RPS25 , RPS26 , RPS27 , RPS27A , RPS28 , RPS29 , RRM1 , RRM2 , RSC1A1 , RXRA , ACSM3 , SARS , SAT1 , MSMO1 , SC5D , SCD , SCO1 , SCP2 , SDC1 , SDC2 , SDC4 , SDHA , SDHB , SDHC , SDHD , SGSH , SHMT1 , SHMT2 , SI , ST3GAL1 , ST3GAL2 , ST3GAL4 , ST3GAL3 , SLC2A1 , SLC2A2 , SLC2A3 , SLC2A4 , SLC2A5 , SLC3A2 , SLC4A1 , SLC5A1 , SLC5A2 , SLC5A3 , SLC5A4 , SLC5A5 , SLC6A7 , SLC6A8 , SLC6A11 , SLC6A12 , SLC9A1 , SLC10A1 , SLC10A2 , SLC16A1 , SLC19A1 , SLC25A1 , SLCO1A2 , SLC22A1 , SLC22A3 , SLC22A2 , SMARCD3 , SMPD1 , SMPD2 , SMS , SNAP25 , SOAT1 , SORD , SP1 , SPR , SQLE , SRD5A1 , SRD5A2 , AKR1D1 , SREBF1 , SREBF2 , SRM , STAR , SULT1E1 , ELOVL4 , STK11 , SULT1A2 , STX1A , STXBP1 , SULT1A1 , SULT1A3 , SULT1C2 , SULT2B1 , SUOX , SULT2A1 , ABCC8 , SURF1 , MED22 , VAMP2 , SYT5 , TALDO1 , TAT , TAZ , TBL1X , TBXAS1 , MLX , TCN1 , TCN2 , TDO2 , TEAD1 , TEAD4 , TEAD3 , TH , THRSP , TK1 , TK2 , TKT , TM7SF2 , TPH1 , TPI1 , TPMT , TPO , TPR , TPTE , TSHB , TST , TTR , TXN , TXNRD1 , TYMS , TYR , TYRP1 , UBA52 , UBB , UBC , UCP1 , UCP2 , UCP3 , UGCG , UGDH , UGP2 , UGT2B4 , UGT2B7 , UGT2B10 , UGT2B15 , UGT2B17 , UGT8 , UCK2 , UMPS , NR1H2 , UPP1 , UQCRB , UQCRC1 , UQCRC2 , UQCRFS1 , UQCRH , UROD , UROS , VLDLR , XDH , LRP8 , HSD17B8 , EPM2A , AIMP2 , SEM1 , NUP214 , CUBN , SLC25A16 , PDHX , AAAS , SLC7A5 , NCOA3 , PUDP , PNPLA4 , ACOX2 , ACOX3 , HYAL3 , PIP5K1A , PIP5K1B , PIP4K2B , PLA2G6 , PLA2G10 , SLC25A11 , BBOX1 , SOAT2 , GNPAT , TEAD2 , RAE1 , PIK3R3 , NDST2 , LIPF , DDO , CYP4F2 , CHST1 , AGPS , DEGS1 , KMO , PDXK , AKR7A2 , SLC25A12 , PLA2G4C , PLPP1 , PLPP2 , PLPP3 , AOC3 , AKR1C3 , ABCB11 , NCOA1 , ALDH4A1 , HYAL2 , DGAT1 , B4GALT4 , B4GALT3 , B4GALT2 , B3GALNT1 , ABCC3 , MBTPS1 , CDS2 , MTMR1 , FBP2 , PEX11A , SUCLG2 , SUCLG1 , SUCLA2 , INPP4B , CES2 , IQGAP1 , GMPS , HDAC3 , SYNJ1 , SYNJ2 , VNN2 , VNN1 , SPHK1 , SGPL1 , SLC5A6 , CPNE3 , MTMR3 , MTMR2 , CPNE1 , GYG2 , KYNU , MGAM , WASL , SLC25A14 , CH25H , RPL14 , AIP , NFS1 , PAPSS2 , PAPSS1 , MTMR6 , MTMR7 , MTMR4 , SLC16A3 , COX7A2L , HACD1 , VAPB , VAPA , LRAT , CACNA2D2 , AIMP1 , MAPKAPK2 , MED14 , B4GALT6 , B4GALT5 , NDST3 , RPL23 , CPNE6 , ADIPOQ , PPT2 , COX5A , GRHPR , LIPG , SLC22A13 , CIAO1 , HS6ST1 , MED21 , FADS2 , CYP7B1 , ABCG2 , CHST2 , MED23 , MED17 , MED26 , MED27 , MED7 , GSTO1 , GGPS1 , PCYT1B , CHST3 , MED20 , SLC25A27 , PGS1 , PSMF1 , AKAP5 , SPTLC2 , EEF1E1 , TECR , PTGES , ATP5MF , MINPP1 , NR1D1 , CLOCK , ENTPD4 , PITPNM1 , NCOR1 , NCOR2 , GDA , ABCG1 , GNA14 , NUP155 , SEC24C , PLCH2 , HS2ST1 , LPIN2 , SDC3 , PPIP5K1 , NUP93 , PTDSS1 , IP6K1 , NUP58 , PSMD6 , MED24 , SEC24D , POM121 , OSBPL2 , FIG4 , ARNT2 , LPGAT1 , XYLB , HS3ST4 , HS3ST3B1 , HS3ST3A1 , HS3ST2 , HS3ST1 , SLC23A2 , SLC23A1 , THRAP3 , MED12 , MED13 , NR1H4 , NUP153 , SCO2 , MED6 , NAALAD2 , ACOT8 , GNPDA1 , MED16 , ABCC5 , NR1H3 , GPC6 , COL4A3BP , UST , NUBP2 , LRPPRC , TRAP1 , NAMPT , AASS , LPCAT3 , SLC25A13 , SLC25A15 , PSME3 , PSMD14 , PLIN3 , COQ7 , GPHN , GLYAT , BCKDK , AKR1A1 , B3GNT3 , BPNT1 , CEPT1 , PEMT , ST3GAL6 , RAPGEF3 , YAP1 , CDIPT , SEC24B , LYPLA1 , ACAA2 , ECI2 , ATP5PD , SLC25A17 , SEC23A , CARM1 , NCOA2 , AGPAT1 , AGPAT2 , SPTLC1 , SLC19A2 , NPC2 , MTHFS , SLCO1B1 , PAICS , ATP5MG , PMVK , CSPG5 , B3GNT2 , GNB5 , EBP , CERS1 , UGT2B11 , PTGES3 , NUP50 , AHCYL1 , MTHFD2 , SEC24A , STARD10 , NEU3 , ALDH1L1 , FTCD , HPSE , CYP46A1 , SLC26A1 , PPARGC1A , LYVE1 , PNPLA6 , UGT2A1 , STARD3 , SERINC3 , ACOT2 , UQCR11 , SLC27A5 , SLC27A3 , SLC27A2 , GLIPR1 , LIAS , B4GAT1 , SLC35D2 , RAPGEF4 , KERA , NUPL2 , HIBADH , PLA2G16 , NUDT4 , NUDT5 , NUDT3 , TREH , INMT , RPL35 , CA5B , CHP1 , CYP4F8 , B4GALT7 , CTRC , ACOT7 , MGLL , CHSY1 , PLEKHA6 , INPP5F , ARSG , SACM1L , PLA2R1 , RPIA , SCAP , PTGR1 , AKR7A3 , NT5C2 , PLCH1 , NCOA6 , NMNAT2 , CDK19 , NUP205 , SLC35D1 , GPD1L , LPIN1 , RGL1 , PSME4 , ACSBG1 , NUP210 , PLCB1 , DDHD2 , PPIP5K2 , NUP160 , ACSL6 , SIN3B , MAN2B2 , ESYT1 , MED13L , PIP5K1C , MLYCD , SLC44A1 , GCAT , ETHE1 , QPRT , ISCU , CES3 , HAAO , NUP188 , RPL13A , NNT , PIK3R5 , SLC16A8 , CHST5 , DDAH2 , ARL2BP , DDAH1 , PDSS1 , ACOT9 , AMACR , CA14 , NUP62 , PLD3 , PRKD3 , BHMT2 , PITPNB , PISD , PGLS , TNFAIP8 , SULT4A1 , PRKD2 , SUMF2 , RPL36 , MPC2 , MTHFD1L , NDUFAF3 , WWTR1 , SIN3A , NUDT13 , MMACHC , TKFC , LRP10 , ACOT11 , OSBPL3 , GLCE , HACL1 , DECR2 , LDLRAP1 , PHGDH , B3GAT3 , TIAM2 , KCNG2 , HIBCH , PLA2G2D , AK5 , FGF21 , GAPDHS , OPLAH , TPK1 , ACAD8 , ANKRD1 , PPA2 , B3GAT1 , UQCRQ , ATP5S , INPP5J , CPNE7 , NDOR1 , CHIA , GLS2 , NMRK2 , GNMT , SULT1C4 , COQ2 , TNFRSF21 , MMADHC , SULT1B1 , MOCS3 , HPGDS , ANGPTL3 , MCAT , MAT2B , SLCO1B3 , ACAD9 , NDUFAF4 , MED4 , ORMDL2 , N6AMT1 , MYLIP , CYP2S1 , UQCR10 , ZDHHC8 , GRHL1 , NPC1L1 , UBIAD1 , PYCR2 , HILPDA , DSE , CERS2 , DMGDH , LRP12 , PSAT1 , SH3KBP1 , PLA2G2E , NT5C , PIK3R4 , RRM2B , G0S2 , PLA2G3 , DUOX2 , CHST11 , PNPLA8 , NSDHL , SLC35B3 , MED31 , COQ6 , RPS27L , NOSIP , DERA , APIP , NDUFA13 , CRYL1 , MLXIPL , SEPSECS , ADIPOR1 , ABHD5 , NDUFAF1 , RDH11 , RPL26L1 , SAR1B , ANGPTL4 , INSIG2 , HSD17B12 , SLC45A2 , AADAT , CYB5R4 , HSD17B11 , HSD17B14 , HAO2 , DCXR , PLCE1 , TACO1 , ACP6 , GLTP , COX16 , PDZD11 , NT5C3A , PIPOX , GMPR2 , CD320 , ECSIT , TIMMDC1 , CYP39A1 , SLC25A37 , MBTPS2 , CHST15 , PLA1A , CSAD , PRKAG2 , IP6K2 , ISYNA1 , HSD17B7 , HACD3 , TRMT112 , LARS , SCLY , RAB14 , GDE1 , AZIN1 , MED15 , LSR , LIPT1 , FAM96B , MPC1 , OAZ3 , CYB5R2 , ACSL5 , CYB5R1 , CMPK1 , UPB1 , RTEL1 , INPP5K , GNG13 , COQ3 , NUDT9 , PANK1 , NUP54 , BCO1 , DUOX1 , CYCS , GNG2 , HAO1 , PLEKHA5 , CHPF2 , UGT2B28 , SMOX , HMGCLL1 , NDUFB11 , UGT1A8 , UGT1A7 , UGT1A6 , UGT1A5 , UGT1A9 , PARP14 , UGT1A4 , UGT1A1 , UGT1A3 , CRLS1 , CROT , PDP1 , MED18 , ELOVL2 , CYP2W1 , LPCAT2 , PARP16 , HRASLS2 , NMRK1 , ACSM5 , MARC2 , MOCOS , SLC52A1 , PDPR , MED9 , PNPO , NUDT11 , NADSYN1 , TMLHE , ETNK2 , PANK4 , ADI1 , NUDT15 , PGM2 , ACOXL , PI4K2B , OLAH , SPTLC3 , RFK , AGPAT5 , ACER3 , ABHD10 , CHDH , PI4K2A , CSGALNACT2 , NDUFAF7 , ETNK1 , CHST12 , SMPD3 , DHTKD1 , STAB2 , MED29 , SMPD4 , VAC14 , NDC1 , FAR2 , NAXD , NUP133 , CNDP2 , AGK , LMBRD1 , CSGALNACT1 , PECR , ACOT13 , TMEM126B , ACSS2 , ANGPTL8 , APOBR , APOM , NDUFA12 , GNG12 , SLC50A1 , GPCPD1 , KYAT3 , CTPS2 , CHST7 , CYP26B1 , INPP5E , ASAH2 , SPHK2 , AGPAT3 , AGPAT4 , BDH2 , STARD7 , MCCC1 , NT5M , PARP6 , ADPRM , CHPT1 , AKR1B10 , COQ9 , CIAPIN1 , ENTPD7 , PNPLA2 , PDSS2 , HRASLS , NUP107 , LYRM4 , SLC44A2 , CEMIP , NMRAL1 , AS3MT , ESYT2 , AHRR , SERINC1 , PDP2 , NCEH1 , CARNS1 , PITPNM2 , PLEKHA4 , GPAM , GBA2 , GBA3 , TRIB3 , G6PC2 , CYP4F11 , SQOR , ENOPH1 , PCTP , MID1IP1 , PLEKHA1 , PLEKHA2 , GNB4 , SLC25A19 , ELOVL5 , PPCDC , HPSE2 , AASDHPPT , EEFSEC , BCAN , ABHD4 , CIDEC , LHPP , MCCC2 , XYLT1 , XYLT2 , DPEP2 , DPEP3 , MMS19 , ABCG5 , ABCG8 , MTMR14 , NARFL , NDST4 , PLA2G2F , HS3ST6 , MARC1 , IPPK , CERK , LMF1 , ARV1 , NMNAT1 , CYP3A43 , ELOVL1 , ETNPPL , LPIN3 , AGXT2 , NADK , PYCR3 , PLEKHA3 , AACS , CYP4F12 , VKORC1 , GGCT , NUP37 , SECISBP2 , ELOVL6 , DCTPP1 , CHAC1 , NDUFAF5 , MBOAT7 , FA2H , GDPD3 , THTPA , B3GNT4 , GLB1L , SLC52A2 , CHPF , ADIPOR2 , CERS4 , ACSS3 , TNFAIP8L2 , ARSJ , SRD5A3 , PANK3 , PARP8 , PPCS , TBL1XR1 , ACBD4 , UGT2A3 , AGMAT , PIP4K2C , NUDT18 , PLBD1 , LPCAT1 , NUP85 , L2HGDH , SCD5 , ELOVL7 , PANK2 , PTGES2 , ASRGL1 , MOGAT2 , CHD9 , COQ10B , ACSF2 , NUBPL , RUFY1 , HSD3B7 , ITPKC , MED28 , FLAD1 , PNPLA3 , COASY , SLC19A3 , ACAD10 , SLC44A4 , STARD5 , CPTP , CYB5B , DDHD1 , SLC25A32 , PTDSS2 , SGPP1 , GDPD5 , PLA2G12A , ACSBG2 , AMN , MED25 , SLC25A28 , SEH1L , PITPNM3 , ELOVL3 , ADPGK , CHST9 , UCK1 , NUDT12 , PARP9 , ESYT3 , BCO2 , SLC25A2 , STARD3NL , BRIP1 , ACAD11 , FAR1 , MRI1 , MED10 , COQ5 , ACBD6 , FAM120B , ACSS1 , MT4 , NT5C1A , DGAT2 , MCEE , CREB3L3 , GPT2 , PLEKHA8 , GPAT3 , PLCD4 , ABHD14B , CBR4 , PARP10 , MFSD2A , ADO , COX14 , PHYKPL , SLC45A3 , HELZ2 , SELENOI , PLCZ1 , SLC25A21 , HS6ST2 , MED30 , PIP4P1 , CERS5 , GGTLC2 , LMF2 , ACBD5 , ACY3 , IDI2 , NDUFAF2 , DSEL , GLYATL1 , LDHAL6B , G6PC3 , B3GNT7 , NT5C1B , COQ10A , NAPRT , TPTE2 , ORMDL1 , ORMDL3 , GNG8 , TGS1 , FDX2 , MED8 , PLCD3 , CHST14 , SLC46A1 , SLC52A3 , AZIN2 , CYP2U1 , CYGB , OSBPL1A , OSBPL5 , OSBPL6 , OSBPL7 , OSBPL8 , OSBPL9 , OSBPL10 , PTPMT1 , NOSTRIN , COX20 , MOGAT1 , ACSM1 , APOA5 , RPL39L , THEM4 , HRASLS5 , IP6K3 , PSTK , GSTO2 , PNLIPRP3 , CYP2R1 , TPH2 , AK7 , PLD4 , ADSSL1 , PSMB11 , ACOT4 , DEGS2 , HYKK , PLA2G4E , ACSM2A , GGT6 , AFMID , SLC5A10 , ACER1 , TNFAIP8L1 , NDUFA11 , CYP4F22 , B3GALT6 , SLC44A3 , FAM213B , NAXE , FITM2 , NUP35 , MBOAT2 , NEU4 , ACMSD , SGPP2 , UROC1 , NUDT16 , GLYCTK , GNPDA2 , ENPP6 , PPARGC1B , UGT3A1 , CMBL , STARD4 , ACOT12 , B3GAT2 , NDUFAF6 , ADHFE1 , GPAT4 , CARNMT1 , RPS4Y2 , RPL10L , ACSM6 , LIPJ , PSMA8 , AMDHD1 , SLC2A14 , PTGR2 , PIK3R6 , STARD6 , LIPI , PNPLA5 , GPAT2 , PLB1 , UPP2 , PPM1L , PPM1K , ARSK , MBOAT1 , VKORC1L1 , TDH , AK8 , FAAH2 , AWAT1 , AWAT2 , LDHAL6A , ALDH1L2 , SLC5A8 , FITM1 , ADAL , NAGS , PHOSPHO1 , SPTSSB , CHST13 , MMAA , SGMS2 , UGT3A2 , IDO2 , NUDT10 , SPTSSA , ABHD3 , PAOX , ADCY4 , ACSF3 , SLC5A9 , PIKFYVE , LIPH , DHFR2 , RPL22L1 , PLD6 , HACD2 , CERS3 , SLC44A5 , MED19 , FOLH1B , GLYATL2 , AK9 , GSTA5 , PRPS1L1 , GPC2 , HS3ST5 , AKR7L , TECRL , IPMK , LCLAT1 , CERS6 , LPCAT4 , TMEM86B , PLA2G4F , PCSK9 , SERINC5 , SGMS1 , IL4I1 , HS6ST3 , PLA2G4D , NUDT7 , GDPD1 , THEM5 , CYP4A22 , SUMF1 , CYP4V2 , COX18 , MMAB , CHSY3 , GPIHBP1 , ENPP7 , GADL1 , ARSI , ZDHHC21 , ACER2 , LIPM , CYP26C1 , ACSM4 , LOC344967 , HSD17B13 , MOGAT3 , DGAT2L6 , ARSH , SLC35B2 , SERINC2 , ACSM2B , NUP43 , NMNAT3 , GSTK1 , NDUFS7 , ASPG , PNPLA7 , AGRN , SLC27A1 , CA13 , ENTPD8 , NHLRC1 , LIPT2 , TNFAIP8L3 , GLYATL3 , IYD , NUDT19 , AGMO , MED11 , C7orf76 , HACD4 , ACBD7 , CTRB2 , MTHFD2L , AKR1B15 , CHAC2 , CKMT1A , UGT2A2 , CYB5RL , SERINC4 , ACOT1 , ACOT6 , LIPK , LIPN , DGAT2L7P , FABP9 , FABP12 , GSTT2B , MIR631 , MIR639 , D2HGDH , MIR671 , POM121C , PLA2G4B , MIR1281 , MIR1908 , MIR3607 , MIR3620 , MIR3658 , LOC100506136 , LHX4-AS1 , MIR4647 , MIR4709 , MIR4651 , MIR4691 , MIR4761 , CYP3A7-CYP3A51P ,