description
Glucose is the major form in which dietary sugars are made available to cells of the human body. Its breakdown is a major source of energy for all cells, and is essential for the brain and red blood cells. Glucose utilization begins with its uptake by cells and conversion to glucose 6-phosphate, which cannot traverse the cell membrane. Fates open to cytosolic glucose 6-phosphate include glycolysis to yield pyruvate, glycogen synthesis, and the pentose phosphate pathway. In some tissues, notably the liver and kidney, glucose 6-phosphate can be synthesized from pyruvate by the pathway of gluconeogenesis

external resources
NCBI:1269959
REACTOME:R-HSA-70326

genes
AGL , ALDOA , ALDOB , ALDOC , BPGM , CALM1 , CALM2 , CALM3 , SLC25A10 , ENO1 , ENO2 , ENO3 , FBP1 , GAA , GAPDH , GBE1 , GCK , GOT1 , GOT2 , GPI , GYG1 , GYS1 , GYS2 , HK1 , HK2 , HK3 , MDH1 , MDH2 , PC , PCK1 , PCK2 , PFKFB1 , PFKFB2 , PFKFB3 , PFKFB4 , PFKL , PFKM , PFKP , PGAM1 , PGAM2 , PGK1 , PGK2 , PGM1 , PHKA1 , PHKA2 , PHKB , PHKG1 , PHKG2 , PKLR , PKM , PPP1R3C , PPP2CA , PPP2CB , PPP2R1A , PPP2R1B , PPP2R5D , PRKACA , PRKACB , PRKACG , PYGB , PYGL , PYGM , RPS27A , SLC25A1 , TPI1 , UBA52 , UBB , UBC , UGP2 , EPM2A , SLC25A11 , SLC25A12 , FBP2 , GYG2 , GNPDA1 , SLC25A13 , GAPDHS , PGM2 , ADPGK , GNPDA2 , NHLRC1 ,