description
DNA synthesis occurs in the S phase, or the synthesis phase, of the cell cycle. The cell duplicates its hereditary material, and two copies of the chromosome are formed. As DNA replication continues, the E type cyclins shared by the G1 and S phases, are destroyed and the levels of the mitotic cyclins rise

external resources
NCBI:1269777
REACTOME:R-HSA-69242

genes
CCND1 , CCNA2 , CCNE1 , CCNH , CDC6 , CDC25A , CDC25B , CDK2 , CDK4 , CDK7 , CDKN1A , CDKN1B , CKS1B , DNA2 , FEN1 , LIG1 , MAX , MCM2 , MCM3 , MCM4 , MCM5 , MCM6 , MCM7 , MNAT1 , MYC , ORC1 , ORC2 , ORC4 , ORC5 , PCNA , POLA1 , POLD1 , POLD2 , POLE , POLE2 , PRIM1 , PSMA1 , PSMA2 , PSMA3 , PSMA4 , PSMA5 , PSMA6 , PSMA7 , PSMB1 , PSMB2 , PSMB3 , PSMB4 , PSMB5 , PSMB6 , PSMB7 , PSMB8 , PSMB9 , PSMB10 , PSMC1 , PSMC2 , PSMC3 , PSMC4 , PSMC5 , PSMC6 , PSMD1 , PSMD2 , PSMD3 , PSMD4 , PSMD5 , PSMD7 , PSMD8 , PSMD9 , PSMD10 , PSMD11 , PSMD12 , PSMD13 , PSME1 , PSME2 , PTK6 , RAD21 , RB1 , RFC1 , RFC2 , RFC3 , RFC4 , RFC5 , RPA1 , RPA2 , RPA3 , RPS27A , SKP1 , SKP2 , UBA52 , UBB , UBC , WEE1 , SMC1A , CDC45 , CUL1 , CCNA1 , SMC3 , CCNE2 , PSMF1 , GINS1 , PSMD6 , PSME3 , PSMD14 , STAG1 , POLD3 , STAG2 , PDS5B , WAPL , PSME4 , PDS5A , ORC6 , ORC3 , POLA2 , FZR1 , GINS2 , POLD4 , GINS3 , CDT1 , GINS4 , MCM8 , CDCA5 , ESCO1 , PSMB11 , PSMA8 , ESCO2 ,