description
Nicotinate (niacin) and nicotinamide are precursors of the coenzymes nicotinamide-adenine dinucleotide (NAD+) and nicotinamide-adenine dinucleotide phosphate (NADP+). When NAD+ and NADP+ are interchanged in a reaction with their reduced forms, NADH and NADPH respectively, they are important cofactors in several hundred redox reactions. Nicotinate is synthesized from 2-amino-3-carboxymuconate semialdehyde, an intermediate in the catabolism of the essential amino acid tryptophan (Magni et al. 2004)

external resources
NCBI:1270154
REACTOME:R-HSA-196807
PUBMED:14704851

genes
PARP4 , BST1 , CD38 , CYP8B1 , NNMT , NT5E , PTGIS , PTGS2 , SLC22A13 , NAMPT , NMNAT2 , QPRT , NMRK2 , PARP14 , PARP16 , NMRK1 , NADSYN1 , NAXD , PARP6 , NMNAT1 , NADK , PARP8 , NUDT12 , PARP9 , PARP10 , NAPRT , NAXE , SLC5A8 , NMNAT3 ,