description
This group of reactions is responsible for: 1) the breakdown of amino acids; 2) the synthesis of urea from ammonia and amino groups generated by amino acid breakdown; 3) the synthesis of the ten amino acids that are not essential components of the human diet; and 4) the synthesis of related nitrogen-containing molecules including carnitine and creatine.Transport of these molecuels across lipid bilayer membranes is annotated separately as part of the module on "transmembrane transport of small molecules"

external resources
NCBI:1270158
REACTOME:R-HSA-71291

genes
AANAT , ACADSB , ACAT1 , AGXT , AHCY , ALDH9A1 , AMD1 , AMT , ARG1 , ARG2 , ASL , ASMT , ASNS , ASPA , ASS1 , ALDH7A1 , AUH , BCAT1 , BCAT2 , BCKDHA , BCKDHB , BHMT , CBS , KYAT1 , CDO1 , CGA , CKB , CKM , CKMT1B , CKMT2 , CPS1 , CRYM , SLC25A10 , CTH , DAO , DARS , DBH , DBT , DCT , DDC , NQO1 , DIO1 , DIO2 , DIO3 , DLAT , DLD , DLST , EPRS , FAH , FAU , FOLH1 , GAMT , GATM , GCDH , GCSH , GCLC , GCLM , GLDC , GLS , GLUD1 , GLUD2 , GLUL , GOT1 , GOT2 , GPT , GSR , GSTZ1 , HSD17B10 , HAL , HDC , HGD , HNMT , HPD , IARS , IDO1 , IVD , KARS , RPSA , MARS , MAT1A , ALDH6A1 , MTAP , MTR , MTRR , NDUFAB1 , RPL10A , NNMT , OAT , OAZ1 , OAZ2 , OCA2 , ODC1 , OGDH , OTC , PAH , PCBD1 , PDHA1 , PDHB , PNMT , PRODH , PSMA1 , PSMA2 , PSMA3 , PSMA4 , PSMA5 , PSMA6 , PSMA7 , PSMB1 , PSMB2 , PSMB3 , PSMB4 , PSMB5 , PSMB6 , PSMB7 , PSMB8 , PSMB9 , PSMB10 , PSMC1 , PSMC2 , PSMC3 , PSMC4 , PSMC5 , PSMC6 , PSMD1 , PSMD2 , PSMD3 , PSMD4 , PSMD5 , PSMD7 , PSMD8 , PSMD9 , PSMD10 , PSMD11 , PSMD12 , PSMD13 , PSME1 , PSME2 , PSPH , PYCR1 , ALDH18A1 , QARS , QDPR , RARS , RPL3 , RPL3L , RPL4 , RPL5 , RPL6 , RPL7 , RPL7A , RPL8 , RPL9 , RPL10 , RPL11 , RPL12 , RPL13 , RPL15 , RPL17 , RPL18 , RPL18A , RPL19 , RPL21 , RPL22 , RPL23A , RPL24 , RPL26 , RPL27 , RPL30 , RPL27A , RPL28 , RPL29 , RPL31 , RPL32 , RPL34 , RPL35A , RPL36AL , RPL37 , RPL37A , RPL38 , RPL39 , RPL41 , RPL36A , RPLP0 , RPLP1 , RPLP2 , RPS2 , RPS3 , RPS3A , RPS4X , RPS4Y1 , RPS5 , RPS6 , RPS7 , RPS8 , RPS9 , RPS10 , RPS11 , RPS12 , RPS13 , RPS14 , RPS15 , RPS15A , RPS16 , RPS17 , RPS18 , RPS19 , RPS20 , RPS21 , RPS23 , RPS24 , RPS25 , RPS26 , RPS27 , RPS27A , RPS28 , RPS29 , SARS , SAT1 , SHMT1 , SLC3A2 , SLC5A5 , SLC6A7 , SLC6A8 , SLC6A11 , SLC6A12 , SMS , SRM , SUOX , TAT , TDO2 , TH , TPH1 , TPO , TSHB , TST , TXNRD1 , TYR , TYRP1 , UBA52 , AIMP2 , SEM1 , PDHX , SLC7A5 , BBOX1 , DDO , KMO , ALDH4A1 , KYNU , RPL14 , PAPSS2 , PAPSS1 , AIMP1 , RPL23 , GRHPR , PSMF1 , EEF1E1 , PSMD6 , NAALAD2 , AASS , SLC25A15 , PSME3 , PSMD14 , BCKDK , FTCD , SERINC3 , LIAS , HIBADH , INMT , RPL35 , PSME4 , GCAT , ETHE1 , HAAO , RPL13A , BHMT2 , RPL36 , PHGDH , HIBCH , ACAD8 , GLS2 , GNMT , PYCR2 , PSAT1 , DUOX2 , RPS27L , APIP , SEPSECS , RPL26L1 , SLC45A2 , AADAT , PIPOX , CSAD , LARS , SCLY , AZIN1 , LIPT1 , OAZ3 , DUOX1 , HAO1 , SMOX , TMLHE , ADI1 , DHTKD1 , CNDP2 , KYAT3 , MCCC1 , NMRAL1 , SERINC1 , CARNS1 , SQOR , ENOPH1 , EEFSEC , MCCC2 , AGXT2 , PYCR3 , SECISBP2 , AGMAT , ASRGL1 , SLC25A2 , MRI1 , GPT2 , ADO , PHYKPL , SLC25A21 , AZIN2 , RPL39L , PSTK , TPH2 , PSMB11 , HYKK , AFMID , ACMSD , UROC1 , CARNMT1 , RPS4Y2 , RPL10L , PSMA8 , AMDHD1 , PPM1K , TDH , NAGS , IDO2 , PAOX , RPL22L1 , FOLH1B , SERINC5 , IL4I1 , GADL1 , SERINC2 , ASPG , LIPT2 , IYD , C7orf76 , CKMT1A , SERINC4 , LOC100506136 ,