description
Polyamines is a family of molecules (i.e. putrescine, spermine, spermidine) derived from ornithine according to a decarboxylation/condensative process. More recently, it has been demonstrated that arginine can be metabolised according to the same pathway leading to agmatine formation. Polyamines are essential for the growth, the maintenance and the function of normal cells. The complexity of their metabolism and the fact that polyamines homeostasis is tightly regulated support the idea that polyamines are essential to cell survival. Multiple abnormalities in the control of polyamines metabolism might be implicated in several pathological processes (Moinard et al., 2005). Legend for the following figure

external resources
NCBI:1270170
REACTOME:R-HSA-351202
PUBMED:11564948
PUBMED:12686127
PUBMED:15784477

genes
AMD1 , ARG1 , ARG2 , ASL , ASS1 , CKB , CKM , CKMT1B , CKMT2 , CPS1 , NQO1 , GAMT , GATM , GOT1 , MTAP , OAZ1 , OAZ2 , ODC1 , OTC , PSMA1 , PSMA2 , PSMA3 , PSMA4 , PSMA5 , PSMA6 , PSMA7 , PSMB1 , PSMB2 , PSMB3 , PSMB4 , PSMB5 , PSMB6 , PSMB7 , PSMB8 , PSMB9 , PSMB10 , PSMC1 , PSMC2 , PSMC3 , PSMC4 , PSMC5 , PSMC6 , PSMD1 , PSMD2 , PSMD3 , PSMD4 , PSMD5 , PSMD7 , PSMD8 , PSMD9 , PSMD10 , PSMD11 , PSMD12 , PSMD13 , PSME1 , PSME2 , SAT1 , SLC6A7 , SLC6A8 , SLC6A11 , SLC6A12 , SMS , SRM , SEM1 , PSMF1 , PSMD6 , SLC25A15 , PSME3 , PSMD14 , PSME4 , APIP , AZIN1 , OAZ3 , SMOX , ADI1 , NMRAL1 , ENOPH1 , AGMAT , SLC25A2 , MRI1 , AZIN2 , PSMB11 , PSMA8 , NAGS , PAOX , C7orf76 , CKMT1A , LOC100506136 ,