description
Abasic sugar phosphate removal via the single nucleotide replacement pathway requires displacement of DNA glycosylase by APEX1, APEX1-mediated endonucleolytic cleavage at the 5' side of the base free deoxyribose residue, recruitment of POLB to the AP site and excision of the abasic sugar phosphate (5'dRP) residue at the strand break (Lindahl and Wood, 1999)

external resources
NCBI:1270362
REACTOME:R-HSA-73930
PUBMED:10583946

genes
APEX1 , POLB ,