description
Double incision at the damaged DNA strand excises the oligonucleotide that contains the lesion from the open bubble. The excised oligonucleotide is ~27-30 bases long. Incision 5' to the damage site, by ERCC1:ERCC4 endonuclease, precedes the incision 3' to the damage site by ERCC5 endonuclease (Staresincic et al. 2009)

external resources
NCBI:1309115
REACTOME:R-HSA-5696400
PUBMED:19279666

genes
PARP1 , DDB1 , DDB2 , ERCC1 , ERCC2 , ERCC3 , ERCC4 , ERCC5 , GTF2H1 , GTF2H2 , GTF2H3 , GTF2H4 , PCNA , POLD1 , POLD2 , POLE , POLE2 , RFC1 , RFC2 , RFC3 , RFC4 , RFC5 , RPA1 , RPA2 , RPA3 , RPS27A , UBA52 , UBB , UBC , XPA , CUL4B , CUL4A , CHD1L , RBX1 , PARP2 , POLD3 , POLK , POLE3 , POLE4 , POLD4 , GTF2H5 ,