description
Three organic anion transporting polypeptides (OATPs; now called solute carrier organic anion transporters, SLCOs) are able to mediate the transport of thryoid hormones, predominantly thyroxine (T4) and triiodothyronine (T3). SLCO1B1 encodes the solute carrier organic anion transporter family member 1B1 (OATP1B1, formerly OATPC), which can also transport bile salts, is mainly expressed in the liver. Defects in SLCO1B1 can cause hyperbilirubinemia, Rotor type (HBLRR; MIM:237450), an autosomal recessive form of primary conjugated hyperbilirubinemia. Mild jaundice, not associated with hemolysis, develops shortly after birth or in childhood (van de Steeg et al. 2012, Sticova & Jirsa 2013, Keppler 2014)

external resources
NCBI:1309189
REACTOME:R-HSA-5619110
NCBI:1309190
REACTOME:R-HSA-5661182
PUBMED:24151358
PUBMED:22232210
PUBMED:24459177

genes
ALB ,