description
Selenocysteine, the 21st genetically encoded amino acid, is the major form of the antioxidant trace element selenium in the human body. In eukaryotes and archaea its synthesis proceeds through a phosphorylated intermediate in a tRNA-dependent fashion. The final step of selenocysteine formation is catalyzed by O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase (SEPSECS) that converts phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec)

external resources
NCBI:1339156
REACTOME:R-HSA-2408557
PUBMED:19747061
PUBMED:20623998
PUBMED:18252769

genes
FAU , RPSA , RPL10A , RPL3 , RPL3L , RPL4 , RPL5 , RPL6 , RPL7 , RPL7A , RPL8 , RPL9 , RPL10 , RPL11 , RPL12 , RPL13 , RPL15 , RPL17 , RPL18 , RPL18A , RPL19 , RPL21 , RPL22 , RPL23A , RPL24 , RPL26 , RPL27 , RPL30 , RPL27A , RPL28 , RPL29 , RPL31 , RPL32 , RPL34 , RPL35A , RPL36AL , RPL37 , RPL37A , RPL38 , RPL39 , RPL41 , RPL36A , RPLP0 , RPLP1 , RPLP2 , RPS2 , RPS3 , RPS3A , RPS4X , RPS4Y1 , RPS5 , RPS6 , RPS7 , RPS8 , RPS9 , RPS10 , RPS11 , RPS12 , RPS13 , RPS14 , RPS15 , RPS15A , RPS16 , RPS17 , RPS18 , RPS19 , RPS20 , RPS21 , RPS23 , RPS24 , RPS25 , RPS26 , RPS27 , RPS27A , RPS28 , RPS29 , SARS , UBA52 , RPL14 , RPL23 , RPL35 , RPL13A , RPL36 , RPS27L , SEPSECS , RPL26L1 , EEFSEC , SECISBP2 , RPL39L , PSTK , RPS4Y2 , RPL10L , RPL22L1 ,