description
Selenocysteine, the 21st genetically encoded amino acid, is the major form of the antioxidant trace element selenium in the human body. In eukaryotes and archaea its synthesis proceeds through a phosphorylated intermediate in a tRNA-dependent fashion. The final step of selenocysteine formation is catalyzed by O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase (SEPSECS) that converts phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec)
external resources
NCBI:1339156
REACTOME:R-HSA-2408557
PUBMED:19747061
PUBMED:20623998
PUBMED:18252769
genes
FAU
,
RPSA
,
RPL10A
,
RPL3
,
RPL3L
,
RPL4
,
RPL5
,
RPL6
,
RPL7
,
RPL7A
,
RPL8
,
RPL9
,
RPL10
,
RPL11
,
RPL12
,
RPL13
,
RPL15
,
RPL17
,
RPL18
,
RPL18A
,
RPL19
,
RPL21
,
RPL22
,
RPL23A
,
RPL24
,
RPL26
,
RPL27
,
RPL30
,
RPL27A
,
RPL28
,
RPL29
,
RPL31
,
RPL32
,
RPL34
,
RPL35A
,
RPL36AL
,
RPL37
,
RPL37A
,
RPL38
,
RPL39
,
RPL41
,
RPL36A
,
RPLP0
,
RPLP1
,
RPLP2
,
RPS2
,
RPS3
,
RPS3A
,
RPS4X
,
RPS4Y1
,
RPS5
,
RPS6
,
RPS7
,
RPS8
,
RPS9
,
RPS10
,
RPS11
,
RPS12
,
RPS13
,
RPS14
,
RPS15
,
RPS15A
,
RPS16
,
RPS17
,
RPS18
,
RPS19
,
RPS20
,
RPS21
,
RPS23
,
RPS24
,
RPS25
,
RPS26
,
RPS27
,
RPS27A
,
RPS28
,
RPS29
,
SARS
,
UBA52
,
RPL14
,
RPL23
,
RPL35
,
RPL13A
,
RPL36
,
RPS27L
,
SEPSECS
,
RPL26L1
,
EEFSEC
,
SECISBP2
,
RPL39L
,
PSTK
,
RPS4Y2
,
RPL10L
,
RPL22L1
,
