description
PTK6 promotes cell motility and migration by regulating the activity of RHO GTPases RAC1 (Chen et al. 2004) and RHOA (Shen et al. 2008). PTK6 inhibits RAS GTPase activating protein RASA1 (Shen et al. 2008) and may be involved in MAPK7 (ERK5) activation (Ostrander et al. 2007, Zheng et al. 2012

external resources
NCBI:1383029
REACTOME:R-HSA-8849471
PUBMED:18829532
PUBMED:17483331
PUBMED:22084245
PUBMED:15572663

genes
RHOA , CRK , DOCK1 , ARHGAP35 , HRAS , KRAS , NF1 , NRAS , PTK6 , PXN , RAC1 , RASA1 , RASA2 , RASAL1 , SYNGAP1 , RASAL2 , BCAR1 , ELMO1 , RASA4 , RASA3 , ELMO2 , RASAL3 , DAB2IP , SPRED1 , SPRED2 , SPRED3 , MIR5004 ,