description
The Josephin domain is present in four human DUBs: Ataxin-3 (ATXN3), ATXN3L, Josephin-1 (JOSD1) and JOSD2. All have been shown to possess DUB activity (Tzveltkov & Breuer 2007, Weeks et al. 2011). Josephin domain DUBs may specialize in distinguishing between polyubiquitin chains of different lengths (Eletr & Wilkinson 2014)

external resources
NCBI:1427864
REACTOME:R-HSA-5689877
PUBMED:23845989

genes
ATXN3 , PRKN , RAD23A , RAD23B , RPS27A , UBA52 , UBB , UBC , VCP , JOSD1 , ATXN3L , JOSD2 ,