description
Direct and indirect interactions of MET with integrins, focal adhesion kinase PTK2 (FAK1), tensin-4 (TNS4) and GTPases RAP1 and RAC1, induce morphological changes that promote cell motility and play an important role in HGF-induced invasiveness of cancer cells (Weidner et al. 1993, Beviglia et al. 1999, Sakkab et al. 2000, Parr et al. 2001, Trusolino et al. 2001, Lamorte et al. 2002, Chen and Chen 2006, Watanabe et al. 2006, Muharram et al. 2014, Murray et al. 2014)

external resources
NCBI:1457799
REACTOME:R-HSA-8875878
PUBMED:24518591
PUBMED:8384622
PUBMED:10521801
PUBMED:12006644
PUBMED:10753869
PUBMED:11478803
PUBMED:16849525
PUBMED:24814316
PUBMED:16782899

genes
CRK , CRKL , GAB1 , GRB2 , RAPGEF1 , HGF , ITGA2 , ITGA3 , ITGB1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMC1 , LAMC2 , MET , PTK2 , RAC1 , RAP1A , RAP1B , SRC , LAMC3 , TNS3 , TNS4 , DOCK7 , LAMA1 , MIR4260 , MIR4758 ,