description
Ferroptosis is a regulated form of cell death and characterized by a production of reactive oxygen species (ROS) from accumulated iron and lipid peroxidation. It can be induced by experimental compounds (e.g.,erastin, RSL3) or clinical drugs(e.g., sulfasalazine, sorafenib) in cancer cell and certain normal cells. It is involved in multiple physiological and pathological processes, such as cancer cell death, neurodegenerative disease, tissue damage and acute renal failure

external resources
NCBI:1510435
KEGG:hsa04216
PUBMED:27314071
PUBMED:28066232
PUBMED:27048822
PUBMED:27791175
PUBMED:26725301
PUBMED:27842067
PUBMED:26775689
PUBMED:27842066
PUBMED:22632964
PUBMED:26405158
PUBMED:28082232
PUBMED:26794443
PUBMED:26436293
PUBMED:27860262
PUBMED:28129536
PUBMED:26653790

genes
ALOX15 , CP , CYBB , ACSL1 , ACSL3 , ACSL4 , FTH1 , FTL , GCLC , GCLM , GPX4 , GSS , HMOX1 , SLC11A2 , PCBP1 , PCBP2 , PRNP , SAT1 , SLC3A2 , TF , TFRC , TP53 , VDAC2 , VDAC3 , NCOA4 , ATG5 , LPCAT3 , ATG7 , ACSL6 , SLC39A14 , SLC7A11 , SLC40A1 , ACSL5 , STEAP3 , SLC39A8 , MAP1LC3B , MAP1LC3A , FTMT , SAT2 , MAP1LC3C ,