description
Phagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is formed when the specific receptors on the phagocyte surface recognize ligands on the particle surface. After formation, nascent phagosomes progressively acquire digestive characteristics. This maturation of phagosomes involves regulated interaction with the other membrane organelles, including recycling endosomes, late endosomes and lysosomes. The fusion of phagosomes and lysosomes releases toxic products that kill most bacteria and degrade them into fragments. However, some bacteria have strategies to escape the bactericidal mechanisms associated with phagocytosis and survive within host phagocytes

external resources
NCBI:153910
KEGG:hsa04145
PUBMED:17637737
PUBMED:18513324
PUBMED:15894272
PUBMED:10684585
PUBMED:18492791
PUBMED:15036145
PUBMED:17245426

genes
ACTB , ACTG1 , ATP6V1A , ATP6V1B1 , ATP6V1B2 , ATP6V0C , ATP6V1C1 , ATP6V1E1 , ATP6V0B , ATP6V1G2 , ATP6V0A1 , ATP6AP1 , C1R , C3 , CALR , CANX , CD14 , CD36 , SCARB1 , COMP , CTSL , CTSS , CYBA , CYBB , DYNC1H1 , DYNC1I1 , DYNC1I2 , DYNC1LI2 , FCAR , FCGR1A , FCGR2A , FCGR2B , FCGR3A , FCGR3B , HLA-A , HLA-B , HLA-C , HLA-DMA , HLA-DMB , HLA-DOA , HLA-DOB , HLA-DPA1 , HLA-DPB1 , HLA-DQA1 , HLA-DQA2 , HLA-DQB1 , HLA-DRA , HLA-DRB1 , HLA-DRB5 , HLA-E , HLA-F , HLA-G , ITGA2 , ITGA5 , ITGAM , ITGAV , ITGB1 , ITGB2 , ITGB3 , ITGB5 , LAMP1 , LAMP2 , M6PR , MBL2 , MPO , MRC1 , MSR1 , NCF2 , NCF4 , NOS1 , OLR1 , PIK3C3 , RAB5A , RAB5B , RAB5C , RAC1 , SFTPD , TAP1 , TAP2 , TFRC , THBS1 , THBS2 , THBS3 , THBS4 , TLR2 , TLR4 , TUBA4A , TUBA3C , TUBB2A , TUBA1A , RAB7A , EEA1 , STX7 , MARCO , ATP6V0E1 , FCGR2C , ATP6V0D1 , HGS , ATP6V1F , VAMP3 , ATP6V1G1 , MRC2 , TCIRG1 , CLEC4M , TLR6 , TUBA1B , TUBB3 , TUBB4A , TUBB4B , SEC61B , CORO1A , PLA2R1 , SEC61G , ATP6V0A2 , STX12 , NOX1 , SEC61A1 , CD209 , NOX3 , ATP6V0A4 , DYNC1LI1 , ATP6V1D , ATP6V1H , TUBA8 , STX18 , SEC61A2 , CLEC7A , COLEC11 , DYNC2H1 , TUBAL3 , TUBB1 , COLEC12 , RILP , TUBB6 , TUBA1C , ATP6V1E2 , TUBA3E , TUBA3D , ATP6V1G3 , ATP6V0E2 , PIKFYVE , TUBB , ATP6V0D2 , ATP6V1C2 , TUBB8 , TUBB2B , NCF1 , SFTPA1 , SFTPA2 ,