description
RNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) via mobile export receptors. The majority of RNAs, such as tRNAs, rRNAs, and U snRNAs, are transported by specific export receptors, which belong to the karyopherin-beta family proteins. A feature of karyopherins is their regulation by the small GTPase Ran. However, general mRNA export is mechanistically different. Nuclear export of mRNAs is functionally coupled to different steps in gene expression processes, such as transcription, splicing, 3'-end formation and even translation

external resources
NCBI:177876
KEGG:hsa03013
PUBMED:10872469
PUBMED:17401408
PUBMED:20733056
PUBMED:11018020
PUBMED:15519698
PUBMED:16314458
PUBMED:15901496
PUBMED:9548260
PUBMED:18313922

genes
CLNS1A , EEF1A1 , EEF1A2 , EIF1AX , EIF2S1 , EIF2B1 , EIF2S3 , EIF4A1 , EIF4A2 , EIF4B , EIF4E , EIF4EBP1 , EIF4EBP2 , EIF4G1 , EIF4G2 , EIF5 , FMR1 , EIF3E , KPNB1 , MAGOH , NCBP1 , NUP88 , NUP98 , PABPC3 , PNN , RAN , RANBP2 , RANGAP1 , UPF1 , SEC13 , SMN1 , SMN2 , SUMO3 , SUMO2 , TPR , UBE2I , SUMO1 , XPO1 , DDX39B , NUP214 , AAAS , FXR1 , RAE1 , GEMIN2 , THOC5 , EIF4EBP3 , EIF3A , EIF3B , EIF3C , EIF3D , EIF3F , EIF3G , EIF3H , EIF3I , EIF3J , EIF4G3 , PABPC4 , EIF2B4 , EIF2B3 , EIF2B2 , EIF2B5 , EIF2S2 , EIF1AY , EIF4E2 , FXR2 , NUP155 , EIF5B , NUP93 , EIF4A3 , NUP58 , POM121 , RBM8A , NUP153 , THOC1 , SNUPN , ALYREF , EIF1 , POP7 , SRRM1 , SAP18 , EIF1B , PRMT5 , TACC3 , NXF1 , RPP30 , RPP38 , PAIP1 , NUP50 , POP4 , RPP40 , RNPS1 , POP1 , NUPL2 , RPP14 , STRAP , DDX20 , XPOT , CASC3 , NCBP2 , ACIN1 , NUP205 , CYFIP1 , NUP210 , NUP160 , NUP188 , NUP62 , GEMIN5 , UPF2 , RNU6-1 , SNORD3B-1 , PABPC1 , CYFIP2 , NXT1 , GEMIN4 , NMD3 , TRNT1 , POP5 , PHAX , NUP54 , RPP25 , GEMIN8 , MAGOHB , ELAC1 , NDC1 , NUP133 , NXT2 , NXF5 , NXF3 , NXF2 , NUP107 , THOC2 , XPO5 , SENP2 , ELAC2 , UPF3B , UPF3A , NUP37 , THOC6 , GEMIN7 , GEMIN6 , RPP21 , NUP85 , THOC7 , PABPC1L , SEH1L , RGPD5 , PYM1 , THOC3 , NUP210L , POM121L2 , TGS1 , NUP35 , PABPC4L , RPP25L , PABPC5 , EIF4E1B , RGPD4 , PABPC1L2A , NUP43 , SUMO4 , RGPD1 , PABPC1L2B , RGPD3 , RGPD8 , NXF2B , EIF3CL , RGPD2 , SNORD3A , SNORD3B-2 , SNORD3C , POM121C ,