description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars. Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV

external resources
NCBI:375172
KEGG:hsa05132
PUBMED:18407067
PUBMED:18411289
PUBMED:18778407
PUBMED:20123714
PUBMED:20158475
PUBMED:19779561
PUBMED:18026123
PUBMED:19930040
PUBMED:12675800
PUBMED:11755407
PUBMED:11489966
PUBMED:19775254
PUBMED:20943123
PUBMED:17690885
PUBMED:16938850
PUBMED:20526845
PUBMED:11567004
PUBMED:17074883
PUBMED:11825778
PUBMED:17071592
PUBMED:16800847
PUBMED:16611232
PUBMED:10499590

genes
ACTB , ACTG1 , RHOG , CASP1 , CD14 , CDC42 , MAPK14 , CSF2 , DYNC1H1 , DYNC1I1 , DYNC1I2 , DYNC1LI2 , FLNA , FLNB , FLNC , FOS , CXCL1 , CXCL2 , CXCL3 , IFNG , IFNGR1 , IFNGR2 , IL1A , IL1B , IL6 , CXCL8 , IL18 , JUN , KLC1 , LBP , MYD88 , MYH9 , MYH10 , NFKB1 , NOS2 , PFN1 , PFN2 , PKN1 , PKN2 , MAPK1 , MAPK3 , MAPK8 , MAPK11 , MAPK9 , MAPK10 , MAPK13 , RAC1 , RELA , ROCK1 , MAPK12 , CCL3 , CCL3L1 , CCL4 , TJP1 , TLR4 , TLR5 , WAS , RAB7A , WASF1 , WASL , ROCK2 , CCL4L2 , ARPC5 , ARPC4 , ARPC3 , ARPC1B , ARPC2 , WASF2 , ARPC1A , PLEKHM2 , PYCARD , PKN3 , DYNC1LI1 , NLRC4 , KLC2 , DYNC2H1 , MYH14 , ARPC5L , RILP , KLC4 , KLC3 , PFN3 , PFN4 , CCL4L1 , CCL3L3 ,